Results 251 to 260 of about 88,024 (314)

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Editorial: Semantics and natural language processing in agriculture. [PDF]

Front Artif Intell
Roche M, Drury BM.
europepmc   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

British Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen, Sean Hennessy, Colleen M. Brensinger, Warren B. Bilker, Laura M. Dember, Todd A. Miano, Tat‐Thang Vo, Allison W. Willis, Charles E. Leonard   +8 more
wiley   +1 more source

Management of chronic kidney disease in a 65-year-old man with diabetes. [PDF]

CMAJ
Dubrofsky L, Cherney DZI, Odutayo A.
europepmc   +1 more source

The ECG in 2026: A 140-Year-Old Tool That Refuses to Be Obsolete. [PDF]

JACC Case Rep
Aronis KN.
europepmc   +1 more source

Toward a common lexicon in gender analysis for global health programs and policies. [PDF]

Health Policy Plan
Morgan R, Kalbarczyk A.
europepmc   +1 more source

Predicting imminent suicide risk in a crisis hotline chat using machine learning. [PDF]

Sci Rep
Levi-Belz Y, Grimland M, Segal-Elbak Y, Munz N, Yeshayahu H, Benatov J, Segal A, Ben Dayan L, Shenfeld I, Gal K.   +9 more
europepmc   +1 more source

Explainable AI for suicide risk detection: gender- and age-specific patterns from real-time crisis chats. [PDF]

Front Med (Lausanne)
Grimland M, Liberman M, Yeshayahu H, Benatov J, Munz N, Segal A, Ben Dayan L, Shenfeld I, Gal K, Levi-Belz Y.   +9 more
europepmc   +1 more source

How professionals in pediatrics change the words they use to mitigate pain: A lexical description after a short hypnosis-based communication training. [PDF]

Br J Pain
Bedu M, Ogez D, Aramideh J, Bőthe B, Levesque A, Rondeau É, Tessier AF, Duval M, Sultan S.   +8 more
europepmc   +1 more source