Results 111 to 120 of about 52,235 (263)
A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
wiley +1 more source
Teorías legitimistas sobre el derecho de propiedad
Teorías legitimistas sobre el derecho de ...
Enrique Gaviria Gutiérrez
doaj
Chemie.KI – Automatisierte Aufgabenbewertung durch trainierte KI‐Modelle
In Schule und Hochschule bearbeiten Lernende in der Regel mehr Aufgaben, als Lehrende korrigieren können. Wo der Mensch an seine Grenzen kommt, kann Künstliche Intelligenz (KI) ansetzen und bei Routineaufgaben unterstützen oder sie auch ganz übernehmen.
Timm Wilke
wiley +1 more source
Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová +5 more
wiley +1 more source
ABSTRACT Despite mounting regulatory pressure and growing scientific consensus on biodiversity loss, most corporate action remains reactive, fragmented, and strategically peripheral. Existing frameworks address what firms should report rather than how they can build the organizational capabilities required to act strategically.
Jacopo Cricchio +4 more
wiley +1 more source
Where early successional forests are more flammable than old‐growth forests, forested landscapes are vulnerable to shifting into ‘fire traps' through positive feedbacks, where fire leads to more fire. These feedbacks are amplified by increased flammability driven by climate change, the presence of non‐native flammable plant species, and slowed ...
George L. W. Perry +4 more
wiley +1 more source
This review summarizes recent advances in electrocatalytic sulfide oxidation (SOR), focusing on catalyst design strategies, reaction system engineering, and pathways for high‐value product generation. The roles of different reduced sulfur species (S2−, HS−, H2S) under various industrial conditions are highlighted, along with approaches to enhance ...
Zhongyuan Wang +4 more
wiley +1 more source
Los temas presupuestarios en el proyecto de Ley de Garantías Económicas
El Proyecto de Ley de Garantías Económicas contiene transformaciones importantes del proceso de asignación de los recursos públicos. Tales cambios se incorporan a la Constitución de la República.
Francisco Esquivel Villegas
doaj
ABSTRACT Water governance is increasingly influenced by a paradox at the nexus of environmental scarcity and food security. Escalating water scarcity crises coincide with geopolitical disruptions that have exposed the fragility of global food supply chains, prompting states to expand domestic food production at the expense of water conservation ...
Alireza Raisi
wiley +1 more source
Tomás de Mercado on slavery: just according to law, unjust in practice
El artículo reconstruye el pensamiento del teólogo dominicano Tomás de Mercado relative a la esclavitud negra. Aunque no sea un tema que él trate muy extensamente, sus consideraciones y argumentos, sobre todo desde el punto de vista de la moral económica
Alfredo Santiago Culleton
doaj

