Results 31 to 40 of about 229,528 (288)
Introduction and aims: Recently, the human regenerative medicine has been departing from the use of xenogeneic materials for the possibility of zoonosis transfer and development of prion infection.
T. Suchánková Kleplová +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Advances in the Pharmacotherapy of Periodontal and Oral Mucosal Diseases
Introduction: There are many of drugs useful for topical or systemic treatment of diseases of periodontal tissue and oral mucous membrane. Their correct administration and efficacy depend strictly on adeqnate of information regarding their properties ...
R. Slezák +5 more
doaj +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Clinical Picture of Candida albicans in the Oral Cavity
Aim of study: The authors describe three types of infections in the oral mucosa caused by fungus Candida albicans. The first type are acute infections, among which we include the acute pseudomembranous candidiasis and the acute erythematous candidiasis ...
J. Minčík +4 more
doaj +1 more source
Bounded Sets in (LF)-Spaces [PDF]
Summary: The behaviour of bounded sets is important in the theory of countable inductive limits of Fréchet spaces, the (LF)-spaces, and its applications. An (LF)-space is called regular if every bounded set is contained and bounded in one of the steps.
Bonet, José, Fernández, Carmen
openaire +2 more sources
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Orofacial Injuries in Children of Primary Schools in Pilsen
Introduction and aim: The injuries are a common important health problem in childhood and their occurrence is often in relation with sport. The first aim of the study was to investigate the prevalence of sport - related injuries in children attending the
V. Merglová +3 more
doaj +1 more source
A practical module system for LF [PDF]
Module systems for proof assistants provide administrative support for large developments when mechanizing the meta-theory of programming languages and logics. We describe a module system for the logical framework LF that is based on two main primitives: signatures and signature morphisms. Signatures are defined as collections of constant declarations,
Florian Rabe 0001, Carsten Schürmann
openaire +2 more sources
Diagnostic Potential of the Synovial Fluid
Introduction: Biochemical changes accompanying intracapsular pathological processes represent potential source of information exploitable in diagnostics, differential diagnostics or monitoring of temporomandibular joint disorders.
V. Schwartzová +3 more
doaj +1 more source

