Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma [PDF]
, 2016 AIM: To analyze colorectal carcinogenesis and age-related DNA methylation alterations of gene sequences associated with epigenetic clock CpG sites.
Barták BK +10 more
core +1 more source
Why Are Autism Spectrum Conditions More Prevalent in Males? [PDF]
, 2011 Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer clues to the etiology of this condition. Although the cause of this bias remains a mystery, we argue that it occurs because ASC is an extreme manifestation of the male ...
Ashwin, Emma +5 more
core +4 more sources
Screening of follicle-stimulating hormone dose-dependent expression genes
浙江大学学报. 农业与生命科学版, 2018 To develop a new and effective method for detection of follicle-stimulating hormone (FSH) bioactivity, porcine follicular granulosa cells were used as experimental materials, and expression of genes in FSH-treated group (40 mIU/mL) and blank control ...
LIU Tian +7 more
doaj +1 more source
Circulating mouse Flk1+/c-Kit+/CD45- cells function as endothelial progenitors cells (EPCs) and stimulate the growth of human tumor xenografts [PDF]
, 2014 BACKGROUND: Endothelial progenitor cells (EPCs) have been demonstrated to have stem-cell like as well as mature endothelial functions. However, controversy remains as to their origins, immunophenotypic markings, and contribution to the tumor vascular ...
J Brown, Jeffery S Russell
core +2 more sources
Perturbations in Lineage Specification of Granulosa and Theca Cells May Alter Corpus Luteum Formation and Function [PDF]
, 2019 Anovulation is a major cause of infertility, and it is the major leading reproductive disorder in mammalian females. Without ovulation, an oocyte is not released from the ovarian follicle to be fertilized and a corpus luteum is not formed.
Abedel-Majed, Mohamed A. +3 more
core +1 more source
Correction: The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns [PDF]
, 2009 Correction to Dolan J, Walshe K, Alsbury S, Hokamp K, O'Keeffe S, Okafuji T, Miller SF, Tear G, Mitchell KJ: The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns.
Guy Tear +8 more
core +2 more sources
Olfactomedin1 (Olfm1) in fallopian tube may modulate tubal ectopic pregnancy in humans: evidence from Immunohistochemistry and an in vitro coculture model [PDF]
, 2010 Conference Theme: The Intersection Between Genetics, Genomics, and Reproductive BiologyOlfactomedins are secretary glycoprotein constituted in the extracellular matrix (ECM) of various cell types.
Ho, PC +3 more
core +1 more source
The forkhead transcription factor, FOXP3: a critical role in male fertility in mice. [PDF]
, 2014 Fertility is dependent on the hypothalamic-pituitary-gonadal axis. Each component of this axis is essential for normal reproductive function. Mice with a mutation in the forkhead transcription factor gene, Foxp3, exhibit autoimmunity and infertility.
Ellsworth, Buffy S +8 more
core +2 more sources
DNA methylation-based age prediction and telomere length in white blood cells and cumulus cells of infertile women with normal or poor response to ovarian stimulation. [PDF]
, 2018 An algorithm assessing the methylation levels of 353 informative CpG sites in the human genome permits accurate prediction of the chronologic age of a subject.
Bedard, Jenna +7 more
core +1 more source
A genomic atlas of human adrenal and gonad development [version 2; referees: 4 approved] [PDF]
, 2017 BACKGROUND: In humans, the adrenal glands and gonads undergo distinct biological events between 6-10 weeks post conception (wpc), such as testis determination, the onset of steroidogenesis and primordial germ cell development.
Achermann, JC +9 more
core +4 more sources