Results 91 to 100 of about 6,588,977 (309)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Functional organic 7,7,8,8‐tetracyanoquinodimethane artificial layers for the dendrite suppressed lithium metal anodes

Electron
The large‐scale industrialization of lithium metal (Li), as a potential anode for a high energy density energy storage system, has been hindered by dendrite growth. The construction of an artificial solid electrolyte interphase layer featuring high ionic
Qing Liu, Zhiyong Zheng, Peixun Xiong, Chun Huang, Shengyang Huang, Baohuai Zhao, Yongan Wu, Yi Zhang, Bo‐Kyong Kim, Xu Yu, Ho Seok Park   +10 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Elimination of “Voltage Noise” of Poly (Ethylene Oxide)-Based Solid Electrolytes in High-Voltage Lithium Batteries: Linear versus Network Polymers

iScience, 2020
Summary: Frequently, poly(ethylene oxide) (PEO)-based solid polymer electrolytes (SPEs) reveal a failure with high-voltage electrodes, e.g. LiNi0.6Mn0.2Co0.2O2 in lithium metal batteries, which can be monitored as an arbitrary appearance of a “voltage ...
Gerrit Homann, Lukas Stolz, Martin Winter, Johannes Kasnatscheew   +3 more
doaj   +1 more source

Construction of Co3O4/ZnO Heterojunctions in Hollow N‐Doped Carbon Nanocages as Microreactors for Lithium–Sulfur Full Batteries

Advanced Science, 2023
Lithium–sulfur (Li–S) batteries are promising alternatives of conventional Li‐ion batteries attributed to their remarkable energy densities and high sustainability.
Biao Wang, Yilun Ren, Yuelei Zhu, Shaowei Chen, Shaozhong Chang, Xiaoya Zhou, Peng Wang, Hao Sun, Xiangkang Meng, Shaochun Tang   +9 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Interfacial Study on Solid Electrolyte Interphase at Li Metal Anode: Implication for Li Dendrite Growth

, 2016
aDepartment of Materials Science and Engineering, Penn State University, University Park, Pennsylvania 16802, USA bDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, Michigan 48824, USA cDepartment of ...
Zhe Liu, Y. Qi, Yuxiao Lin, Lei Chen, Peng Lu, Long-Qing Chen   +5 more
semanticscholar   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Design Principles for Self-forming Interfaces Enabling Stable Lithium Metal Anodes

, 2019
The path toward Li-ion batteries with higher energy-densities will likely involve use of thin lithium metal (Li) anode (
Chiang, Yet-Ming, Li, Linsen, Pan, Sam, Pande, Vikram, Viswanathan, Venkatasubramanian, Wang, David, Wen, Bohua, Zhu, Yingying   +7 more
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