Results 61 to 70 of about 63,803 (294)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Synergizing Conformal Lithiophilic Granule and Dealloyed Porous Skeleton toward Pragmatic Li Metal Anodes

Small Science, 2022
Li metal is regarded as one of the most promising anodes for next‐generation rechargeable batteries. Nonetheless, infinite volume change and severe dendrite growth impede its practicability.
Zixiong Shi, Zhongti Sun, Xianzhong Yang, Chen Lu, Shuo Li, Xiaoyu Yu, Yifan Ding, Ting Huang, Jingyu Sun   +8 more
doaj   +1 more source

Effect of Ga₂O₃ Addition on the Properties of Garnet-Type Ta-Doped Li₇La₃Zr₂O₁₂ Solid Electrolyte

Batteries, 2022
Garnet-type Ta-doped Li7La3Zr2O12 (LLZO) ceramic solid electrolytes with Ga2O3 additive were synthesized using a conventional solid-state reaction process.
Yusuke Yamazaki, Shotaro Miyake, Keigo Akimoto, Ryoji Inada   +3 more
doaj   +1 more source

Equicontinuity and Li–Yorke pairs of dendrite maps

Dynamical Systems, 2020
In this paper, relationships between equicontinuity of a dendrite map f on Λ ( f ) , absence of Li–Yorke pairs, collection of minimal sets and regularly recurrent points are investigated.
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

On the Potential of the Excluded Volume and Auto-Correlation as Neuromorphometric Descriptors

, 2005
This work investigates at what degree two neuromorphometric measurements, namely the autocorrelation and the excluded volume of a neuronal cell can influence the characterization and classification of such a type of cells.
Barbosa, Boycott, Cajal, Coelho, Cook, Costa, Costa, Costa, Costa, Fernandez, Isihara, Jones, L. da F. Costa, M.S. Barbosa, McLachlan, Morigiwa, Morita, Onsager, Rodieck, Smith, V. Coupez, Wässle   +21 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Crossover Scaling in Dendritic Evolution at Low Undercooling

, 1999
We examine scaling in two-dimensional simulations of dendritic growth at low undercooling, as well as in three-dimensional pivalic acid dendrites grown on NASA's USMP-4 Isothermal Dendritic Growth Experiment.
A. A. Wheeler, A. A. Wheeler, A. Karma, Afina Lupulescu, D. A. Kessler, D. A. Kessler, E. Ben-Jacob, E. Brener, G. Caginalp, G. Caginalp, G. Caginalp, J. A. Warren, J. B. Collins, J. Ignés-Mullol, J. S. Langer, Jeffrey C. LaCombe, Jonathan Dantzig, K. R. Elder, M. B. Koss, M. E. Glicksman, M. E. Glicksman, M. Muschol, Martin E. Glicksman, Matthew B. Koss, N. Provatas, N. Provatas, N. Provatas, Nigel Goldenfeld, Nikolas Provatas, Q. Li, R. Almgren, R. Almgren, R. J. Braun, R. Kobayashi, Robert Almgren, S.-C. Huang, S.-L. Wang, U. Bisang, Y. Pomeau   +38 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Mg Doped Li–LiB Alloy with In Situ Formed Lithiophilic LiB Skeleton for Lithium Metal Batteries

Advanced Science, 2020
High energy density lithium metal batteries (LMBs) are promising next‐generation energy storage devices. However, the uncontrollable dendrite growth and huge volume change limit their practical applications. Here, a new Mg doped Li–LiB alloy with in situ
Chen Wu, Haifeng Huang, Weiyi Lu, Zengxi Wei, Xuyan Ni, Fu Sun, Piao Qing, Zhijian Liu, Jianmin Ma, Weifeng Wei, Libao Chen, Chenglin Yan, Liqiang Mai   +12 more
doaj   +1 more source