Results 101 to 110 of about 636,258 (345)
Advanced Science, EarlyView.AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie +14 more
wiley +1 more source
Investigating Stagnant Air Conditions in Almaty: A WRF Modeling Approach
AtmosphereThis study investigates stagnant atmospheric conditions in Almaty, Kazakhstan, a city nestled within a complex terrain. These conditions, characterized by weak local winds and inversion layers, trap pollutants within the city, particularly during winter.
Tatyana Dedova +4 more
doaj +1 more source
JAMA psychiatry, 2019 Key Points Question Does genetic liability to insomnia, hypersomnia, and chronotype differentiate subtypes of bipolar disorder? Findings In this case-control study of 4672 participants with bipolar disorder and 5714 control participants, individuals with
Katie J S Lewis +16 more
semanticscholar +1 more source
Hazardous Activities and Civil Strict Liability: The Regulator’s Dilemma [PDF]
This paper addresses the conditions for setting up strict civil liability schemes. For that it compares the social efficiency of two main civil liability regimes usually enforced to protect the environment: the strict liability regime and the “capped ...
Gérard Mondello
core
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
On the Existence and Efficiency of Equilibria Under Liability Rules [PDF]
While the focus of mainstream economic analysis of liability rules remains on negligence liability, recently some legal scholars have argued for the sharing of liability.
Ram Singh
core +2 more sources
Risky Activities and Strict Liability Rules: Delegating Safety [PDF]
This paper studies the delegation of activities that pose serious risks to health and the environment in an economy regulated by strict liability schemes. Strict liability induces judgment-proof possibilities.
Gérard Mondello
core
Advanced Science, EarlyView.A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou +12 more
wiley +1 more source
Accidents Waiting to Happen: Liability Policy and Toxic Pollution Releases [PDF]
Proponents of environmental policies based on liability assert that strict liability imposed on polluters induces firms to handle hazardous wastes properly.
Austin, David, Alberini, Anna
core +2 more sources
The Sustainability Liability: Potential Negative Effects of Ethicality on Product Preference
, 2010 Manufacturers are increasingly producing and promoting sustainable products (i.e., products that have a positive social and/or environmental impact). However, relatively little is known about how product sustainability affects consumers’ preferences. The
M. Luchs +3 more
semanticscholar +1 more source