Results 221 to 230 of about 636,258 (345)

The ultimate forgery: A semiotic deconstruction of large language models as engines of simulated selfhood

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Information science rests on a compact: its mediating signs maintain a traceable relation to what they describe. Large language models (LLMs) break it architecturally, generating discourse that is statistically plausible yet epistemically ungrounded, while standard metrics (precision, recall, relevance) cannot detect the rupture.
Martin Thellefsen, Alon Friedman
wiley   +1 more source

AI product liability under EU and Canadian laws. [PDF]

Front Artif Intell
Sarabdeen J.
europepmc   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Research on intellectual property rights and legal liability definition of artificial intelligence-assisted pediatric disease diagnosis system. [PDF]

Front Public Health
Yang Z, Yang W.
europepmc   +1 more source

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes   +2 more
wiley   +1 more source

Genetic liability to ADHD and migraine risk: Mendelian randomization evidence for behavioural and psychiatric pathways

Luo Y, Dardani C, Wootton RE, Sanderson ECM, Stergiakouli E.   +4 more
europepmc   +1 more source

Mendelian randomization analysis of the causal relationship between allergic rhinitis and depression and underlying mediation mechanisms. [PDF]

World Allergy Organ J
Zhang S, Wang R, Weng J, Li M, Shi M, Wei J, Ye L, Huang X, Huang W, Qu S.   +9 more
europepmc   +1 more source

Translational development of crisugabalin for neuropathic pain

British Journal of Clinical Pharmacology, EarlyView.
Abstract Crisugabalin (HSK16149) is a next‐generation α2δ ligand developed to preserve the mechanistic rationale of gabapentinoids while refining target engagement and exposure‐related tolerability constraints. We performed a translational review of molecular/structural studies, in vivo pharmacology and behavioural safety assessments, phase I clinical ...
Rafael Batista João, Jilly Octoria Tagore Chan, Luísa Mendes Araújo, André Batista João, Raquel Mattos Filgueiras, Paulo César Ragazzo   +5 more
wiley   +1 more source

Racial gaps without racism: How English universities frame inequality in access and participation plans

British Educational Research Journal, EarlyView.
Abstract Racial inequalities are pervasive in higher education despite concerted efforts to redress issues of access, progression and continuation. Little attention has been paid to how universities themselves construct race within their policy texts.
Benjamin Hart, Mirna Šumatić
wiley   +1 more source