Results 61 to 70 of about 1,253,261 (308)

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

Advanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang, Ji Chen, Jinfeng Han, Wei Cheng, Jiang Qiu, Jianfeng Feng, Simon Eickhoff, Deniz Vatansever   +7 more
wiley   +1 more source

Use of omic heating technology in the process of processing fruits and vegetables. Overview of the subject field

Пищевые системы
The modern consumer prefers natural products with minimal processing, which allows maximum preservation of the nutritional value of the product and fresh taste and aroma.
L. Ch. Burak, A. N. Sapach
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

EXPERIENCE OF INTRODUCTION OF THE AUTOMATED SYSTEM "NAVIGATION AND MANAGEMENT" ON THE BASIS OF SATELLITE NAVIGATION AND ITS INTERACTION WITH SINGLE AUTOMATED CONTROL SYSTEM OF "UKRZALIZNYTSIA" FREIGHT TRANSPORTATION IN THE CONDITIONS OF THE TEST SITE SOUT

Nauka ta progres transportu, 2008
The issues of use of satellite technology on railway transport are considered upon the results of testing the specimen of computer-aided system «Navigation and Control» at the test proving ground of Pivdenna Railway.
M. M. Titov, Yu. M. Borushko, S. B. Semenov, Ye. V. Liashenko   +3 more
doaj  

Investigating Stagnant Air Conditions in Almaty: A WRF Modeling Approach

Atmosphere
This study investigates stagnant atmospheric conditions in Almaty, Kazakhstan, a city nestled within a complex terrain. These conditions, characterized by weak local winds and inversion layers, trap pollutants within the city, particularly during winter.
Tatyana Dedova, Larissa Balakay, Edige Zakarin, Kairat Bostanbekov, Galymzhan Abdimanap   +4 more
doaj   +1 more source

Methodological Approaches to Validation of Therapeutic Recombinant Proteins Production Based on the Quality by Design Concept

Биопрепараты: Профилактика, диагностика, лечение, 2018
Validation of production processes based on the Quality by Design (QbD) principles calls for thorough scientific understanding of the processes and enhancement of their stability by implementation of new technologies.
N. V. Stratonova, A. S. Lisov, A. N. Morozov, D. V. Tyupa, R. A. Khamitov   +4 more
doaj   +1 more source

Book Reviews [PDF]

, 1991
Reviews of the following two books: VALUING HEALTH Risks. COSTS, AND BENEFITS FOR ENVIRONMENTAL DECISION MAKING (P. Brett Hammond and Rob Coppock, eds.) THE LIABILITY MAZE: THE IMPACT OF LIABILITY LAW ON SAFETY AND INNOVATION (Peter W.
Field, Thomas G., Jr.
core   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Optimized Low-Carbon Economic Dispatch of Island Microgrids via an Improved Sine–Cosine Algorithm

Energies
Under the environment of globalized energy restructuring and achieving the goal of “peak carbon and carbon neutrality”, this paper proposes an optimal scheduling method based on the improved cosine algorithm for island microgrids, which relies on diesel ...
Naihua Feng, Peng Yu, Guanbao Yang, Qian Jia   +3 more
doaj   +1 more source