Results 231 to 240 of about 84,205 (294)

Targeting the SIRT1‐NAT10‐GABABR1 Axis: A Novel Epitranscriptomic Approach to Mitigate Sevoflurane‐Induced Cognitive Impairment in Aging

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The study reveals that NAT10 enhances GABABR1 mRNA stability via ac4A modification, leading to excessive inhibitory synaptic activation. In aged rats, sevoflurane contributes to cognitive impairment by inhibiting Sirt1 and neuronal autophagy, which subsequently disrupts energy metabolism.
Xin Xie   +3 more
wiley   +1 more source

Molecular Mechanisms and Therapeutic Potential of DJ‐1 in Skeletal Muscle Homeostasis and Disease

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
DJ‐1 protein functions as a redox‐sensing guardian in skeletal muscle by coordinating antioxidant defense, mitochondrial homeostasis, metabolic adaptation, and anti‐atrophy signaling. Enhancing its function holds promise as a potential therapeutic strategy for muscle atrophy, ALS, and metabolic myopathies.
Yue Zhang   +5 more
wiley   +1 more source

Human infection with Candidatus Rickettsia jingxinensis: First identification and clinical characteristics. [PDF]

open access: yesPLoS Negl Trop Dis
Gao Y   +10 more
europepmc   +1 more source

Harnessing Population Genomics, Gut Microbiota, and Environmental DNA Surveillance for the Conservation of Chinese Spotted Seals in a Changing World

open access: yesEcology and Evolution, Volume 16, Issue 2, February 2026.
Marine mammals are sentinel species for ocean and human health. Multiple anthropogenic and environmental stressors threaten these organisms, particularly China's spotted seals, which have experienced significant decline over the past half‐century. Our review reveals low genetic diversity in Chinese spotted seal populations.
Shuzhen Li   +4 more
wiley   +1 more source

LMO4 promotes OSCC progression by inducing RAB17 degradation and ferroptosis resistance. [PDF]

open access: yesCell Death Dis
Fan J   +13 more
europepmc   +1 more source

Maize Knows Friends or Foes? The Dark Side of Trichoderma asperellum as a Maize Ear Rot Pathogenic Fungus

open access: yes
Plant Biotechnology Journal, EarlyView.
Weixiang Wang   +16 more
wiley   +1 more source

Case Report and Literature Review: Intrathyroid Thymic Carcinoma

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 2, Page 461-464, February 2026.
This case report highlights the challenges in diagnosing intrathyroid thymic carcinoma (ITTC), a rare thyroid tumor, and underscores the importance of postoperative pathology for confirmation. The study emphasizes the good prognosis of ITTC with appropriate surgical management.
Jia‐Yue Sun   +3 more
wiley   +1 more source

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