Results 61 to 70 of about 69,838 (265)

Tubocapsenolide A Overcomes Oxaliplatin Resistance in Colorectal Cancer by Targeting PLK1 to Impair CEP55–ESCRT‐Associated Vesicular Damage Clearance

Advanced Science, EarlyView.
Oxaliplatin‐resistant colorectal cancer cells utilize a previously unappreciated PLK1‐CEP55‐ESCRT‐driven vesicular extrusion mechanism to clear L‐OHP‐induced cellular damage. The natural withanolide Tubocapsenolide A directly targets and inhibits PLK1 to disrupt this specific damage‐clearance machinery. This blockade induces severe nucleolar stress and
Yueying Yang, Jing Liang, Lu Wang, Hongyan Zhang, Zhiruo Zhang, Yang Liu, Rui Zhu, Wen Xu, Shaohua Xu, Dejuan Sun, Ke Xiang, Yali Wang, Zhimin Fan, Zheng Wang, Hua Li, Lixia Chen   +15 more
wiley   +1 more source

香港酒店建築物能耗表現的基準分析

, 2010
The Liaoning (Dalian)-Hong Kong Joint Symposium 2010, Dalian, China, 2-3 July 2010. In Proceedings of Joint Symposium, 2010, p.
Wong, MKF, Hui, SCM
core  

Distribution of real estate financial risks in Liaoning Province.

Distribution of real estate financial risks in Liaoning Province.
Jian-Lin Yuan (18469114), Nan Jing (5884445)   +1 more
core   +1 more source

Unidentified Liaoning fossil specimen.

, 2015
An unidentifiable specimen from a Liaoning rock slab containing a Microraptor specimen (LVH 0026). No diagnostic bones are visible on the specimen surface, but laser penetration into the matrix induced fluorescence in multiple teeth and scales, making ...
Xing Xu (244136), Thomas G. Kaye (53092), David A. Burnham (745940), Enpu Gong (745941), Michael Pittman (412822), Paul C. Sereno (36583), Amanda R. Falk (745939), Larry D. Martin (147481), Yinan Wang (478812)   +8 more
core   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Fleece metrology of Liaoning cashmere goats

, 1991
Fleece metrology of Liaoning cashmere ...
M An (13428717), Y Jiang (7730723), B McGregor (13791427)   +2 more
core  

FIGURE 2 in A new eucryptodiran turtle from the Early Cretaceous Jiufotang Formation of western Liaoning, China

, 2010
FIGURE 2. Liaochelys jianchangensis gen. et sp. nov. (PMOL-AR00160, holotype), from the Early Cretaceous Jiufotang Formation of Lamadong, Jianchang City, western Liaoning Province, China.Published as part of Zhou, Chang-Fu, 2010, A new eucryptodiran ...
Zhou, Chang-Fu
core   +1 more source

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source

Intelligent Field‐Adaptive Electrohydrodynamic Printing for Curved Conformal Electronics

Advanced Science, EarlyView.
To mitigate residual‐charge accumulation and spatial electric‐field variations during electrohydrodynamic printing on curved insulating substrates, an intelligent field‐adaptive framework combines alternating‐electric‐field modulation, equivalent electrical gap characterization, and machine‐learning‐guided parameter inversion and pathwise regulation ...
Chang Liu, Yiwen Feng, Xu Chen, Kaiwen Chen, Ran Zhang, Xiaopeng Zhang, Liujia Suo, Xiangji Chen, Zefei Li, Fengshu Wang, Ruixuan Xu, Shuaiwu Liu, Shiwen Liang, Lingjie Kong, Dazhi Wang   +14 more
wiley   +1 more source

Engineering Polar Nanoregions in COFs via Controlled Symmetry Breaking Toward Piezocatalysis

Angewandte Chemie, EarlyView.
Polar nanoregions (PNRs) are engineered within covalent organic frameworks via asymmetric grafting of highly polar polyfluoroalkyl chains, which enables controlled symmetry breaking. These randomly oriented artificial PNRs dynamically respond to mechanical stimuli and impart relaxation behavior to the COFs (TFB‐TAPT‐FA).
Ge Yan, Yixuan Wang, Xiaodong Sun, Liberty L. Mguni, Shuai Zhang, Shiyuan Liu, Xue Zhou, Lingfeng Zhu, Yali Yao, Hongwei Huang, Liqun Ye, Xinyi Yang, Bo Zou, Tianyi Ma   +13 more
wiley   +2 more sources