Results 131 to 140 of about 6,125,574 (326)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Organizational Climate Assessment of Medical Libraries with International ClimateQUAL Tool in North of Iran

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2013
BACKGROUND AND OBJECTIVE: An effective organizational climate that is defined as a collection of characteristics of an organization is an important resource for improving staff’s mental health that affects their morale, contribution in decision-making ...
M Yaminfirooz, F Noshinfard, N Hariri
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Progress Toward a National Serials Data System [PDF]

open access: yes, 1970
published or submitted for ...
Adams, Scott
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Support and Content (internal and external) analysis ofacademic libraries websites’ of Iranian Universities of Medical Sciences

open access: yesمدیریت اطلاعات سلامت, 2014
Introduction: Universities of Medical Sciences Academic Libraries websites’ have an important role in interaction and offering services for users. The aim of present study was the assessment of Support and Content analysis of academic libraries websites’
Elham Ahmadi   +2 more
doaj  

Special Libraries, January 1936 [PDF]

open access: yes, 1934
Volume 27, Issue 1https://scholarworks.sjsu.edu/sla_sl_1936/1000/thumbnail ...
Special Libraries Association
core   +6 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Special Libraries, February 1966 [PDF]

open access: yes, 1964
Volume 57, Issue 2https://scholarworks.sjsu.edu/sla_sl_1966/1001/thumbnail ...
Special Libraries Association
core   +4 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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