Results 161 to 170 of about 5,919,368 (372)
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
The Tensor-Core Beamformer: A High-Speed Signal-Processing Library for Multidisciplinary Use [PDF]
arXivBeamforming is a well-known technique to combine signals from multiple sensors. It has a wide range of application domains. This paper introduces the Tensor-Core Beamformer: a generic, optimized beamformer library that harnesses the computational power of GPU tensor cores to accelerate beamforming computations.
arxiv
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
مدیریت اطلاعات سلامت, 2014 Introduction: Universities of Medical Sciences Academic Libraries websites’ have an important role in interaction and offering services for users. The aim of present study was the assessment of Support and Content analysis of academic libraries websites’
Elham Ahmadi +2 more
doaj
Special Libraries, March 1948 [PDF]
, 1947 Volume 39, Issue 3https://scholarworks.sjsu.edu/sla_sl_1948/1002/thumbnail ...
Special Libraries Association
core +3 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
The New Knowledge Environment: Quality Initiatives in Health Sciences Libraries [PDF]
, 1996 published or submitted for ...
Nagle, Ellen
core
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2006 On behalf of the management board of the AGMB in 2003-2005 the AGMB task force on financing of medical libraries dealt with several questions relating to the present legal situation of hospital libraries. The following report summarises the activities of
Klein, Diana
doaj