Results 201 to 210 of about 259,653 (293)
Monoclonal antibody generation by controlled immunoglobulin gene rearrangements. [PDF]
Murayama A+7 more
europepmc +1 more source
High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires+4 more
wiley +1 more source
Making an impact: the new 2024 Medical Library Association research agenda. [PDF]
Ascher M+4 more
europepmc +1 more source
This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im+9 more
wiley +1 more source
Integrating physical units into high-performance AI-driven scientific computing. [PDF]
Wang C, He S, Luo S, Huan Y, Wu S.
europepmc +1 more source
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett+13 more
wiley +1 more source
Making the most of Artificial Intelligence and Large Language Models to support collection development in health sciences libraries. [PDF]
Portillo I, Carson D.
europepmc +1 more source
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang+14 more
wiley +1 more source
The evolution and application of RNA-focused small molecule libraries. [PDF]
Taghavi A+6 more
europepmc +1 more source