Results 261 to 270 of about 5,959,618 (329)

Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D‐Printed Titanium Truss

Advanced Healthcare Materials, EarlyView.
This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee, Ali Kiapour, Brendan D. Stoeckl, Ellen Y. Zhang, Matthew R. Begley, Jarod Oldham, Lewis Harrison, Jessee Hunt, Robert L. Mauck, Su Chin Heo   +9 more
wiley   +1 more source

Cell type-specific purifying selection of synonymous mitochondrial DNA variation. [PDF]

Proc Natl Acad Sci U S A
Lareau CA, Maschmeyer P, Yin Y, Gutierrez JC, Dhindsa RS, Gribling-Burrer AS, Zielinski S, Hsieh YH, Nitsch L, Dimitrova V, Nalbant B, Buquicchio FA, Abay T, Stickels RR, Ulirsch JC, Yan P, Wang F, Miao Z, Sandor K, Daniel B, Liu V, Mendez PL, Knaus P, Meyer M, Greenleaf WJ, Kundaje A, Smyth RP, Munschauer M, Ludwig LS, Satpathy AT.   +29 more
europepmc   +1 more source

DNA Barcoding‐Enabled Tracking of Lipid Nanoparticles: Drug‐Loading‐Dependent Biodistribution and Tumor Microenvironment Targeting

Advanced Healthcare Materials, EarlyView.
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu, Rui Chen, Xing Wang, Dawei Liu, Yun liu, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Mutational and low-coverage whole genome sequencing identifies actionable DNA repair alterations in prostate cancer plasma DNA. [PDF]

Sci Rep
Virga A, Urbini M, Polano M, Petracci E, Tedaldi G, Gurioli G, Marisi G, Angeli D, Ambrosini-Spaltro A, De Luca G, Cangini I, Zampiga V, Cenacchi G, Toffoli G, Casadei C, Cursano MC, Conteduca V, De Giorgi U, Ulivi P.   +18 more
europepmc   +1 more source

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes. [PDF]

Cell Host Microbe
Rodriguez-Rodriguez L, Pfister J, Schuck L, Martin AE, Mercado-Santiago LM, Tagliabracci VS, Forsberg KJ.   +6 more
europepmc   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

NNLM\SCR Contract Awarded, Vol.14 (4) July - August 2001 [PDF]

, 2001
Houston Academy of Medicine-Texas Medical Center Library
core   +1 more source

Fine tuned CatBoost machine learning approach for early detection of cardiovascular disease through predictive modeling. [PDF]

Sci Rep
Hamid M, Hajjej F, Alluhaidan AS, Bin Mannie NW.   +3 more
europepmc   +1 more source

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source