Results 111 to 120 of about 2,351,922 (324)
Special Libraries, March 1925 [PDF]
Volume 16, Issue 3https://scholarworks.sjsu.edu/sla_sl_1925/1002/thumbnail ...
Special Libraries Association
core +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
A Virtual Standoff – Using Q Methodology to Analyze Virtual Reference
Objective - To develop an exploratory understanding of reference librarians’ perceptions of virtual reference. Methods – Q methodology was used to uncover points of view about virtual reference.
Aaron Shrimplin, Susan Hurst
doaj +1 more source
Special Libraries, March 1917 [PDF]
Volume 8, Issue 3https://scholarworks.sjsu.edu/sla_sl_1917/1002/thumbnail ...
Special Libraries Association
core +4 more sources
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
As library systems across Canada begin to grapple with the implications community-led service planning has on program and service development, new tools are being developed to assist library staff.
Kenneth William Williment+1 more
doaj +1 more source
Special Libraries, July-August 1953 [PDF]
Volume 44, Issue 6https://scholarworks.sjsu.edu/sla_sl_1953/1005/thumbnail ...
Special Libraries Association
core +2 more sources
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source