Results 111 to 120 of about 4,474,959 (386)
Special Libraries, March 1937 [PDF]
, 1936 Volume 28, Issue 3https://scholarworks.sjsu.edu/sla_sl_1937/1002/thumbnail ...
Special Libraries Association
core +5 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Special Libraries, December 1924 [PDF]
, 1924 Volume 15, Issue 10https://scholarworks.sjsu.edu/sla_sl_1924/1009/thumbnail ...
Special Libraries Association
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Special Libraries, February 1929 [PDF]
, 1927 Volume 20, Issue 2https://scholarworks.sjsu.edu/sla_sl_1929/1001/thumbnail ...
Special Libraries Association
core +3 more sources
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture
Genome Research, 2012 Improvements in technology have reduced the cost of DNA sequencing to the point that the limiting factor for many experiments is the time and reagent cost of sample preparation.
N. Rohland, D. Reich
semanticscholar +1 more source
, 2023 The Society of Jesus began a tradition of collecting books and curating those collections at its foundation. These libraries were important to both their European sites and their missions; they helped build a global culture as part of early modern European evangelization.
openaire +4 more sources