Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Visibility of Library and Information Science and Science Communication in Iran [PDF]
This study examines how newspapers in Iran have presented library and information science (LIS) to society; how the media understand library and information science as a discipline; and how authors of articles in LIS journals collaborate with members of ...
Zahra Ojagh, Golnessa Galyani Moghaddam
doaj +1 more source
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
Fay B. Kaigler Children\u27s Book Festival [PDF]
The program for the fiftieth annual Fay B. Kaigler Children\u27s Book Festival held on the campus of The University of Southern Mississippi in Hattiesburg, Mississippi in 2017.https://aquila.usm.edu/kaiglergallery/1043/thumbnail ...
Rowell, Karen+2 more
core +16 more sources
Telling Great Stories: An NSDL Content and Communications System for Aggregation, Display, and Distribution of News and Features [PDF]
Education digital libraries contain cataloged resources as well as contextual information about innovations in the use of educational technology, exemplar stories about community activities, and news from various user communities that include teachers, students, scholars, and developers.
arxiv
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Availability of Library Aesthetics for Enhanced Educational Purpose of Library Patronage by Users in Federal University Libraries in South East, Nigeria. [PDF]
The study investigated the availability of library aesthetics for enhanced educational purpose of library patronage by users in federal university libraries in South East, Nigeria. Three specific objectives guided the study.
Enweremadu Isaac, Usuka+2 more
core +3 more sources
Deploying Linked Open Vocabulary (LOV) to Enhance Library Linked Data
Since the advent of Linked Data (LD) as a method for building webs of data, there have been many attempts to apply and implement LD in various settings.
Oh, Sam Gyun+2 more
doaj +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Health Information Seeking Behavior among the Users of Public Libraries in Isfahan City, Iran
Introduction: Investigating the health information seeking behavior of users can help librarians to provide appropriate services, and help public libraries to make effective decisions and plans.
Nasrin Musarezai+2 more
doaj +1 more source