Results 141 to 150 of about 5,432,324 (400)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Evidence-based biomedical research in Sub-Saharan Africa: how library and information science professionals contribute to systematic reviews and meta-analyses. [PDF]

J Med Libr Assoc, 2022
Asubiaro TV, Isioma E.
europepmc   +1 more source

Developing a 21st Century Global Library for Mathematics Research [PDF]

arXiv, 2014
Developing a 21st Century Global Library for Mathematics Research discusses how information about what the mathematical literature contains can be formalized and made easier to express, encode, and explore. Many of the tools necessary to make this information system a reality will require much more than indexing and will instead depend on community ...
arxiv  

Collection Development Policies of Electronic Resources in University Libraries in Southeast Nigeria. [PDF]

, 2018
This paper is an empirical study of collection development policy of electronic resources in university libraries in South East Nigeria. The study ascertains the types of policies guiding electronic resources collection development practices; identifies ...
Ekere, F C, Department of Library and Information Science University of Nigeria Nsukka, Okogwu, Flora Ifeoma   +1 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

From Crisis to Transformation: Lessons Learned and Recommendations for LIS Graduate Programs in Thailand Post-Pandemic

Journal of Information Science Theory and Practice
This study aims to investigate the management of library and information science (LIS) graduate programs in Thailand during the COVID-19 pandemic and highlights the challenges faced by the programs’ chairs, faculty members, and graduate students during ...
Sujira Ammarukleart, Chutima Sacchanand, Nilobon Wimolsittichai, Duangkaew Ngernpoolsap, Jutatip Chanlun   +4 more
doaj   +1 more source

Social Interactive Media Tools and Knowledge Sharing: A Case Study [PDF]

arXiv, 2013
Purpose: Social Media Tools (SMT) have provided new opportunities for libraries and librarians in the world. In academic libraries, we can use of them as a powerful tool for communication. This study is to determine the use of the social interactive media tools [Social Networking Tools (SNT), Social Bookmarking Tools (SBT), Image or Video Sharing Tools
arxiv  

Library and Information Science across Disciplines [PDF]

, 2020
At the heart of library and information science (LIS) is the process of seeking information, gathering and storing it, and then putting it to use - often by its dissemination to others.
Mattock, Lindsay, Shaw, George, Wagner, Travis, Zamir, Hassan, Zimmerman, Margaret   +4 more
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source