Results 121 to 130 of about 232,629 (299)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Building Strong Library Associations (2008-2018) - Module 6 (Library Statistics for Advocacy) [PDF]

open access: yes
The sixth module of Building Strong Library Associations (2008-2018) focused on the use of library statistics in order to support ...
International Federation of Library Associations and Institutions (IFLA)
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Límits i exepcions al dret d'autor per a les biblioteques

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2009
International Federation of Library Associations. Committee on Copyright and other Legal Matters
doaj   +1 more source

Building Strong Library Associations (2008-2018) - Module 7 (Copyright) [PDF]

open access: yes
The seventh module of the Building Strong Library Associations (2008-2018) programme focused on library association engagement in advocacy around ...
International Federation of Library Associations and Institutions (IFLA)
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Current Status of Pakistan Library Association

open access: yesJournal of Information Management and Practices
Oldest and most well-known professional association of librarians and information professionals in Pakistan is the Pakistan Library Association (PLA) founded in 1957 and registered under the Societies Registration Act of 1860.
Nasir Mahmood, Perviaz Ahmad
doaj  

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