Results 111 to 120 of about 2,463,396 (307)
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Framing Collaboration: Archives, IRs, and General Collections [PDF]
Collaborative collecting highlights the opportunity for liaison librarians and archivists in academic libraries to develop an integrated and holistic approach to the successful collection of library materials. Yet as academic libraries become the central
Baillargeon, Tara +3 more
core +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
ISLAMIC EDUCATION INTITUTIONS IN THE CLASSICAL PERIOD (UMAYYAD AND ABBASID PERIODS) [PDF]
Islamic education has existed since the Prophet Muhammad SAW and continues to develop until now. Islam once reached the peak of glory, called the golden age, because, at that time, Islamic education was very developed and produced an extraordinary ...
Faridi, Faridi +2 more
core +1 more source
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Interview with Albert S. Peeling, June 3, 1995
Albert S. Peeling was interviewed on June 3, 1995 by Michael J. Birkner & David Hedrick about his years as a student at Gettysburg College in the class of 1925.
Birkner, Michael J., Peeling, Albert S.
core
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Newspaper of the university of alaska southeast juneau campus [PDF]
Library faces unsure future -- Smoking ban ignites campus controversy -- Student survey secures summer session -- UA students intern in governor's office -- Rotary offers scholarship -- Gissberg forges Pacific Rim Fisheries links -- Microsoft upgrades ...
core
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source

