Results 41 to 50 of about 32,469,295 (310)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Applications of Total Quality Management in Medical Libraries [PDF]

open access: yesTaṣvīr-i salāmat, 2013
​Library is a growing organism. Consistent with social development, the growth of the nations and the impact of technology change, library management and services change as well.
Amane Dadashi Mehrabani   +2 more
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Libraries' Organizational Changes by New Technologies [PDF]

open access: yesتحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2007
As reputed by Ranganatan, Library is an alive and active and active organism, so it may be changed by environmental changes. Today, the level of change in main question instead of what is going to be changed.
Mina Semiromizade
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Public Libraries in the Digital Age: An Indian Perspective

open access: yesInternational Journal of Emerging Research in Engineering, Science, and Management
This paper examines the state and challenges of public libraries in India amid the ongoing digital transformation. With over 75,000 rural and nearly 5,000 urban libraries, India’s public library network plays a crucial role in democratizing information ...
Jogen Sharma
doaj   +1 more source

THE MANAGEMENT OF CHANGE IN ELECTRONIC LIBRARIES [PDF]

open access: yesIFLA Journal, 2001
A cause des changements radicaux en technologie, les bibliotheques sont dans un processus de changement fondamental. Ce texte retrace les changements qui ont eu lieu au cours des ans, et fait quelques pronostics sur le futur. Les obstacles a l'usage accru des technologies sont analyses et expliques.
openaire   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Systematic Reviews and Librarians: A Primer for Managers

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research, 2015
Systematic reviews—and research syntheses in general—are increasing as a form of research. As a result, academic librarians from across disciplines are seeing a growth in the number of requests for library resources and services to support the ...
Genevieve C. Gore, Julie Jones
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

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