Results 31 to 40 of about 322 (120)

Alkali‐Metal Base Catalyzed Electrocyclization of Isoprene Derivatives

Chemistry – A European Journal, Volume 32, Issue 27, 17 July 2026.
Simple and abundant alkali‐metal base catalysis in combination with Lewis basic polyamines enables the electrocyclization of isoprene‐derived trienes to cycloheptadienes under neat conditions. Mechanistic insight supported by DFT guides a scalable route to seven‐membered carbocycles which, after reduction, give saturated cycloalkanes relevant as ...
Mikaël Le Roch, Krzysztof Piech, Aurélien Crochet, Andreu Tortajada   +3 more
wiley   +1 more source

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Shapley Additive Explanation for Local Class Differentiation: Local Explainability for Class Differentiation in Classification Models

Advanced Intelligent Systems, Volume 8, Issue 7, July 2026.
An instance‐level, model‐agnostic explanation of class differentiation is introduced through SHAP‐LCD, linking probability shifts to feature‐wise Shapley contributions. The method operates on tabular and image data and is released in a fully reproducible implementation, offering a transparent way to examine, at each instance, why predictive models ...
Roxana M. Romero Luna, Hugo A. Ordoñez Erazo, Carlos A. Cobos Lozada   +2 more
wiley   +1 more source

Beta‐Thalassemia in Spain: Results From the National Thalassemia Registry and Molecular Analysis of Patients With Transfusion‐Dependent Thalassemia

Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.
This nationwide registry‐based study describes the clinical and molecular characteristics of 78 patients with transfusion‐dependent beta‐thalassemia in Spain. Comprehensive genetic analysis revealed marked molecular heterogeneity, with 24 HBB mutations identified and a predominance of β0 genotypes, alongside generally effective transfusion and iron ...
Ana Villegas, Paloma Ropero, Fernando Ataulfo González, Marta Morado, María Menor, Silvia de la Iglesia, Montserrat López‐Rubio, Eduardo José Salido, Mariola Abío, María Leonor Senent, Valle Recasens, José Manuel Vagace, Cristina Fonte, Jesús María Hernández‐Rivas, José María Raya, Pablo Ríos, Valeria Luciana Peri, Keneth A. Herrera, María Concepción Tenorio, Laura Lo Riso, Juan Tena, María Angustias Molina, Miriam Vara, Isabel Rodríguez, Pilar Ricard, Miguel Gómez, Oana Popa Dusacovschi, Julia María Vidán, Jorge Groiss, Óscar Ferre, Irene Orbe, Rosa María López, Nazaret Ugalde, Manuela Inés Hidalgo, Cristina Hinojosa, Ana Isabel Rodríguez, Esther Herrera, María Josefa Murúzabal, María del Carmen Hernández, Josefa Esperanza Marco, Celina Benavente, Grupo Español de Eritropatología   +41 more
wiley   +1 more source

Združevanje bibliografskih zapisov v COBISS+: začetek novih katalogov v sistemih COBISS

Knjižnica, 2017
Izvleček Skupaj z zasnovo COBISS+ smo želeli začeti postopek prestrukturiranja katalogov v sistemu COBISS po modelu FZBZ, vendar smo se po daljši analizi sedanjih odnosov med zapisi v katalogu in katalogizacijskih pravil omejili na tri odnose; to so ...
Andreja Krajnc Vobovnik, Gordana Mazić
doaj   +1 more source

Stacked Ensemble Model With Explainable AI for Early Detection of Heart Disease

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Heart disease (HD) is still one of the most common causes of death around the world. Early detection is very important, but it is often hard to do because the symptoms are not specific and the models are not very clear. We propose a two‐layer stacked ensemble that combines four base learners—Support Vector Machine, K‐Nearest Neighbors, Naïve ...
Nazmun Nahar, Sanjatul Hasan Siam, Joy Bhowmik, Ayesha Nasrin Ripa, Md. Hasan Imam, Haw Jiunn Woo, Hamid Osman, Mayeen Uddin Khandaker, Shams Forruque Ahmed   +8 more
wiley   +1 more source

Synthesis of a C‐2 Functionalized l‐Iduronic Acid Derivative as a Candidate Pharmacological Chaperone for MPS II (Hunter Syndrome)

Chemistry – An Asian Journal, Volume 21, Issue 11, 15 June 2026.
A C‐2 functionalized l‐iduronic acid derivative was designed and synthesized as a candidate pharmacological chaperone for iduronate‐2‐sulfatase (IDS), the enzyme involved in the lysosomal storage disease MPS II (Hunter syndrome). The synthesis overcomes significant synthetic challenges associated with manipulations of L‐ido scaffolds.
Vaibhavi Nagendra, Shifaza Mohamed, Nicholas W. See, Norbert Wimmer, Daniel Neumann, Paul J. Trim, Marten Snel, Aidan J. Brock, Jack K. Clegg, Neha S. Gandhi, Kim M. Hemsley, Adeline A. Lau, Vito Ferro   +12 more
wiley   +1 more source

Does education policy affect teachers' learning needs? An international comparison of trends in teachers' continuing professional learning needs in secondary schools in Australia, England, Japan and the Netherlands

British Educational Research Journal, Volume 52, Issue 3, Page 1987-2008, June 2026.
Abstract Education policy changes are believed to influence teachers' continuing professional learning (CPL) needs, but there is limited empirical evidence to support these claims. This lack of deep understanding has significant practical implications. This study used a new circular conceptual framework to analyse teachers' CPL needs. Leveraging public
Rikkert M. van der Lans, Remmert Daas, Joost Jansen in de Wal, Elaine Wilson, Noriyuki Inoue, Tracy L. Durksen, Frank Cornelissen   +6 more
wiley   +1 more source

Traceable Traceless Delivery Tags

Helvetica Chimica Acta, Volume 109, Issue 6, June 2026.
ABSTRACT This study elaborates on traceless tags for the thiol‐mediated uptake (TMU) of amine‐containing substrates of interest (SOIs). Traceless tags typically contain linkers that can be enzymatically cleaved to trigger the release of SOIs in their native form.
Julia Moreno, Xudong Ren, Saidbakhrom Saidjalolov, Pierre Josso, Naomi Sakai, Stefan Matile   +5 more
wiley   +1 more source

Identifying Food Packaging Migrants: Current Analytical Capabilities, Challenges, and Future Prospects

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The migration of intentionally and non‐intentionally added substances (IAS/NIAS) from food packaging into foodstuffs presents a significant challenge to consumer health and food safety. Accurate and comprehensive identification of these chemical migrants is therefore paramount.
Xue‐Chao Song, Qi‐Zhi Su, Elena Canellas, Qin‐Bao Lin, Yu Zhou, Cristina Nerin   +5 more
wiley   +1 more source