Results 211 to 220 of about 1,107,317 (288)

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

Advanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao, Hong‐Yi Zhao, Chengyi Li, Hanning Wen, Fang Ke, Qiuxia Li, Miao He, Bo Wen, Zhongwei Liu, Kai Sun, Wei Gao, Duxin Sun   +11 more
wiley   +1 more source

Allelic variation of Avr genes in highly virulent strains explains severe wheat stem rust epidemics. [PDF]

Nat Commun
Spanner RE, Henningsen EC, Langlands-Perry C, Chen J, Lubega J, Matny O, Lewis D, Cheah LC, Su Z, Feist A, Nazareno ES, Li F, Outram MA, Arndell T, Vanhercke T, Virzì N, Luo M, Ayliffe M, Stone E, Kanyuka K, Sperschneider J, Dodds PN, Steffenson BJ, Figueroa M.   +23 more
europepmc   +1 more source

A survey of consumer health reference services policies of academic medical school libraries and veterinary medical school libraries

, 2019
Carol E. Vreeland
openalex   +2 more sources

G4‐Ligand‐Directed PROTACs Unveil DR1 as a Novel Ligand‐Co‐Binding G4‐Protein and Reshape G4‐Dependent Transcription

Advanced Science, EarlyView.
G4‐binding proteins (G4BPs) that specifically co‐bind G4s in the presence of small‐molecule ligands represent a critical but unexplored class of proteins. We introduce G4‐Ligand‐Directed PROTACs (G4L‐TACs), a chemical platform that couples G4 ligands (PDS) to E3 recruiters to selectively degrade these ligand‐co‐binding G4BPs.
Mao‐Lin Li, Shu‐Min Xu, Xin‐Chen Jiang, Le‐Tian Dai, Yu‐Tao Hu, Kai‐Bo Wang, Jia‐Heng Tan, Zhi‐Shu Huang, Shuo‐Bin Chen   +8 more
wiley   +1 more source

Mapping cis- and trans-regulatory target genes of human-specific deletions. [PDF]

Nat Commun
Fair T, Pavlovic BJ, Swope D, Castillo OE, Schaefer NK, Pollen AA.   +5 more
europepmc   +1 more source

Users’ Satisfaction on Library Services in Anna University with Special Reference to Enginerring Colleges at Coimbatore City, Tamil Nadu: A Study

, 2015
S. Chandra Mohan Kumar, S. Chandra Mohan Kumar   +1 more
openalex   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

The impact of digital organizational culture on the performance of university libraries. [PDF]

Sci Rep
Tara N, Ahmad K, Aljarboa S, El-Wahed Khalifa HA, Alburaikan A, Rafi M.   +5 more
europepmc   +1 more source

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

Advanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun, Miji Kim, Wooyeon Shin, Yongjun Park, Kanghwan Kim, Il‐Joo Cho, Jae Won Shim, Min Soo Kim, Sunwoo Lee, Jeongjin Kim, Changhyuk Lee   +10 more
wiley   +1 more source

Genetic data normalization for genomic medicine: a Fast Healthcare Interoperability Resources Genomics reference implementation. [PDF]

J Am Med Inform Assoc
Dolin RH, Todor NM, Shalaby J, Arsalan H, Shah E, Basravi N, Husami A, Rampersad A, Heale BSE, Chamala S.   +9 more
europepmc   +1 more source