Results 51 to 60 of about 1,107,317 (288)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Lightning Presentation: How Discovery Tools Changed Instruction and Reference [PDF]

open access: yes, 2014
In fall 2011, Viterbo University migrated from a legacy ILS and public catalog to a next generation ILS and discovery layer. Learn how the transition to a discovery environment affected reference and instruction services, librarian expectations of ...
Nelson, Jennifer   +1 more
core   +1 more source

Band Alignment in In‐Oxo Metal Porphyrin SURMOF Heterojunctions

open access: yesAdvanced Functional Materials, EarlyView.
Porphyrin core metalation in indium‑oxo SURMOFs enables systematic tuning of band edge positions without altering the crystal structure. First‑principles calculations reveal type‑I and type‑II heterostructures as well as multi‑junction energy cascades, establishing a modular strategy for exciton funneling and charge separation in optoelectronic ...
Puja Singhvi, Nina Vankova, Thomas Heine
wiley   +1 more source

Teaching Students to Fish: Creating a Sustainable Student Peer Research Program

open access: yes, 2015
A Peer Research Mentor (PRM) program was developed at Musselman Library, Gettysburg College to augment traditional reference services and expand library outreach.
Jallas, Mallory R., Smith, Meggan D.
core  

Are there common academic library customer values? [PDF]

open access: yes, 2008
: Purpose – This paper endeavours to provide answers to the following questions: Is there a correlation between what library customers value and the questions asked in benchmarking satisfaction surveys?
McKnight, S
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

The New Technology and Competencies for "The Most Typical of the Activities of Libraries": Technical Services [PDF]

open access: yes, 1983
At a library conference in 1940, William M. Randall called technical services the "most typical of the activities of libraries" "they are..." he said, "the things which librarians do that no one else does the secrets of the craft." 1 In those ...
Henderson, Kathryn Luther
core  

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

open access: yesAdvanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi   +5 more
wiley   +1 more source

PDA Reference Services @ the Library

open access: yesGMS Medizin - Bibliothek - Information, 2008
There is an increasing need felt by the health library users for obtaining accurate, up to date, evidence-based and mobile scientific information in their daily clinical practice. The need to reduce diagnostic errors, save time and achieve the best decision-making for their patients, has became a serious problem to this group of health ...
openaire   +1 more source

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