Results 81 to 90 of about 25,190,607 (340)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Definire gli archivi di ricerca e sostenere la loro protezione: il progetto della biblioteca digitale della Sapienza

open access: yesJLIS.it, 2015
One of the most critical problems for research archives is their definition. Without a common dictionary and a robust conceptual framework, academic research heritage, specifically if in digital form, is at risk; the efforts made for its preservation and 
Maria Guercio, Cecilia Carloni
doaj   +1 more source

Libraries and Research

open access: yesCollege & Research Libraries, 1940
Submitted by Sarah Shreeves (sshreeve@illinois.edu) on 2012-04-19T21:01:40Z No. of bitstreams: 1 crl_02_01_22_opt.pdf: 1253356 bytes, checksum: c041b3e93a48eee16d85254b0ca209f9 (MD5) ; Made available in DSpace on 2012-04-19T21:01:40Z (GMT). No. of bitstreams: 1 crl_02_01_22_opt.pdf: 1253356 bytes, checksum: c041b3e93a48eee16d85254b0ca209f9 (MD5 ...
openaire   +2 more sources

Research in Libraries [PDF]

open access: yesNature, 1878
BEFORE this “voice from Australia” can reach London, I hope that some steps will have been taken towards carrying out Dr. Mallet's valuable suggestion (NATURE, vol. xvi. p. 457) so far as regards the British Museum and other leading European libraries.
openaire   +1 more source

Landmark Report (Vol. 3, no. 8) [PDF]

open access: yes, 1982
Newsletter published by the Landmark Association; this local group advocates the preservation, protection and maintenance of architectural, cultural and archaeological resources in Bowling Green and Warren County ...
Kentucky Library Research Collections,
core   +3 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Library Assessment Research: A Content Comparison from Three American Library Journals

open access: yesPublications, 2018
Improvement of academic library services as an outcome of continuous assessment is an aim of libraries of higher education institutions. Academic libraries are realizing the need to document evidence of their value to the institutions and the patrons ...
Ethan J. Allen   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy