Results 101 to 110 of about 5,186,294 (314)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

TANTANGAN DAN PELUANG PRODI IPII IAIN CURUP DALAM MEWUJUDKAN PUSTAKAWAN ERA 5.0

open access: yesBIBLIOTIKA: Jurnal Kajian Perpustakaan dan Informasi
Penelitian ini mengevaluasi tantangan dan peluang Program Studi Ilmu Perpustakaan dan Informasi Islam (IPII) IAIN Curup dalam mencetak pustakawan profesional di era 5.0.
Rhoni Rodin   +3 more
doaj   +1 more source

“Use” in the Literature of Library and Information Science: A Concept Analysis and Typology [PDF]

open access: yes, 2008
The “use” of information and library resources and services is frequently presented in Library and Information Science LIS) literature as a primitive concept: an idea so fundamental to the theoretical framework at hand as to be indefinable—even when ...
Rachel Anne Fleming-may   +1 more
core  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Library Associates Newsletter: Issue 1 [PDF]

open access: yes, 1975
Issue 1 Contents: Trustees Appointed; Trustees Meet; Program Committee Plans; Library Associates Benefactors; Corporation Members of Library Associates; Library Services for Associates; Special Services for Collectors; Recent Acquisitions; American ...
Lauinger Library
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Library and Information Science Internship

open access: yesPakistan Journal of Information Management & Libraries
This study explores whether Library and Information Science students from three universities who participated in experiential learning through internship programs have identical or different experiences during their internships under selected internship ...
Noel W. Cabfilan   +3 more
doaj  

Об объекте и предмете библиотековедческих исследований

open access: yesБиблиосфера, 2010
The authors treat different approaches to the definition of object and subject in library science investigations, offer their own definition of the notion «the object of library science investigation» as a library process and come to the conclusion, that

doaj  

Research fronts in library and information science in Spain [PDF]

open access: yes, 1998
Publications and author cocitations in library and information science in Spain during the period from 1985 to 1994 were analyzed as a measure of the structure, specificity and composition of research fronts in this country. A cocitation matrix developed
De-Moya-Anegón, Félix   +2 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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