Results 131 to 140 of about 3,998,759 (349)
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source
TANTANGAN DAN PELUANG PRODI IPII IAIN CURUP DALAM MEWUJUDKAN PUSTAKAWAN ERA 5.0
Penelitian ini mengevaluasi tantangan dan peluang Program Studi Ilmu Perpustakaan dan Informasi Islam (IPII) IAIN Curup dalam mencetak pustakawan profesional di era 5.0.
Rhoni Rodin+3 more
doaj +1 more source
Computing with Classical Real Numbers [PDF]
There are two incompatible Coq libraries that have a theory of the real numbers; the Coq standard library gives an axiomatic treatment of classical real numbers, while the CoRN library from Nijmegen defines constructively valid real numbers. Unfortunately, this means results about one structure cannot easily be used in the other structure. We present a
arxiv
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
A New Framework for software Library Investment Metrics [PDF]
Software quality is considered as one of the most important challenges in software engineering. It has many dimensions which differ from users' point of view that depend on their requirements. Therefore, those dimensions lead to difficulty in measuring and defining the software quality properly.
arxiv
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
In this paper, the values of morality in professional field has been discussed. It’s termed as Ethics. The term Ethics is derived from Greek word Ethikos with actually meaning custom or habit. The following paper will aid to determine the fundamental concepts behind ethics in professional field of Library and Information Sciences.
openaire +2 more sources