Results 161 to 170 of about 3,998,759 (349)

NEMO News, Volume 5, Issue 3 [PDF]

open access: yes, 2009
This issue of NEMO News features Announcements, Advice from the Frontlines from Pat Leach, Student Spotlight on Benjamin Shorb, Web 2.0, Contact Info and See our students work!https://digitalcommons.unomaha.edu/nemo/1024/thumbnail ...
Education, UNO Library Science
core   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Library Education and Development Newsletter, Volume 5, Issue 3 [PDF]

open access: yes, 2012
This issue of the Library Education and Development Newsletter features Advice from the Frontlines from Melody Kenney, a Student Spotlight of Beth Eilers, UNO Registration Dates, Announcements, Conferences and Professional Development, and UNO Faculty ...
Education, UNO Library Science
core   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

open access: yesFEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren   +8 more
wiley   +1 more source

FROM E-LIBRARY SCIENCE TO LIBRARY INFORMATION SCIENCE

open access: yesProceedings of Altai State Academy of Culture and Arts, 2020
openaire   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Explicative methods in library science investigations

open access: yesБиблиосфера, 2010
Рассматриваются возможности различных методов для использования в библиотековедческих исследованиях. Особый акцент сделан на ивент-анализе, который позволяет пересмотреть стратегию развития библиотеки и скорректировать планы ее развития.
G. V. Varganova
doaj  

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