This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Impact of specialist palliative care on utilization of healthcare and social services at the end-of-life: a nationwide register-based cohort study. [PDF]
Ahtiluoto SE +8 more
europepmc +1 more source
DATA-DRIVEN LIBRARIES: INTEGRATING ANALYTICS AND EVIDENCE-BASED PRACTICE FOR SERVICE EXCELLENCE
Harihararao Mojjada +1 more
openalex +1 more source
Smart Bioinspired Material‐Based Actuators: Current Challenges and Prospects
This work gathers, in a review style, an extensive and comprehensive literature overview on the development of autonomous actuators based on synthetic materials, bringing together valuable knowledge from several studies. Furthermore, the article identifies the fundamental principles of actuation mechanisms and defines key parameters to address the size
Alejandro Palacios +4 more
wiley +1 more source
Influence of knowledge management practices on librarians' competency in artificial intelligence in tertiary institutions of Lokoja, Kogi State, Nigeria. [PDF]
Yusuf SK +3 more
europepmc +1 more source
This article offers a comprehensive review of topic modeling techniques, tracing their evolution from inception to recent developments. It explores methods such as latent Dirichlet allocation, latent semantic analysis, non‐negative matrix factorization, probabilistic latent semantic analysis, Top2Vec, and BERTopic, highlighting their strengths ...
Pratima Kumari +6 more
wiley +1 more source
A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes. [PDF]
Mameli E +9 more
europepmc +1 more source
Exploring the Impact of Artificial Intelligence on the Modernization of Library Services in Pakistan
Gulzar Ahmed Lakho +7 more
openalex +2 more sources
Real‐Time Control of a Humanoid Robot for Whole‐Body Tactile Interaction
Inspired by human tactile interaction, this work integrates large‐area artificial skin feedback (force and proximity) into real‐time quadratic programming control for humanoids. This enables robots to leverage distributed sensing to manage forces, safely move around unknown and dynamic obstacles, and robustly handle objects with uncertain geometry ...
Simon Armleder +4 more
wiley +1 more source

