Results 241 to 250 of about 6,725,926 (309)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

Impact of specialist palliative care on utilization of healthcare and social services at the end-of-life: a nationwide register-based cohort study. [PDF]

open access: yesEur J Public Health
Ahtiluoto SE   +8 more
europepmc   +1 more source

Smart Bioinspired Material‐Based Actuators: Current Challenges and Prospects

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This work gathers, in a review style, an extensive and comprehensive literature overview on the development of autonomous actuators based on synthetic materials, bringing together valuable knowledge from several studies. Furthermore, the article identifies the fundamental principles of actuation mechanisms and defines key parameters to address the size
Alejandro Palacios   +4 more
wiley   +1 more source

Recent Advancements in Topic Modeling Techniques for Healthcare, Bioinformatics, and Other Potential Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
This article offers a comprehensive review of topic modeling techniques, tracing their evolution from inception to recent developments. It explores methods such as latent Dirichlet allocation, latent semantic analysis, non‐negative matrix factorization, probabilistic latent semantic analysis, Top2Vec, and BERTopic, highlighting their strengths ...
Pratima Kumari   +6 more
wiley   +1 more source

A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes. [PDF]

open access: yesNat Commun
Mameli E   +9 more
europepmc   +1 more source

Exploring the Impact of Artificial Intelligence on the Modernization of Library Services in Pakistan

open access: hybrid
Gulzar Ahmed Lakho   +7 more
openalex   +2 more sources

Real‐Time Control of a Humanoid Robot for Whole‐Body Tactile Interaction

open access: yesAdvanced Intelligent Systems, EarlyView.
Inspired by human tactile interaction, this work integrates large‐area artificial skin feedback (force and proximity) into real‐time quadratic programming control for humanoids. This enables robots to leverage distributed sensing to manage forces, safely move around unknown and dynamic obstacles, and robustly handle objects with uncertain geometry ...
Simon Armleder   +4 more
wiley   +1 more source

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