Results 111 to 120 of about 4,623,855 (303)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Alles dual oder was? Kooperatives, praxisintegrierendes oder praxisbegleitendes Studium in der Bibliotheks- und Informationswissenschaft

open access: yesGMS Medizin – Bibliothek – Information
Strategic staff recruitment has to focus on all phases of the professional biography. It begins with the entry into a professional field through professional training or studies.
Wimmer, Ulla
doaj   +1 more source

Studying Academic Lawyers' Information-Seeking to Inform the Design of Digital Law Libraries [PDF]

open access: yes, 2006
We report findings from the initial phase of our study on legal information seeking, which comprised a series of semi-structured interviews and naturalistic observations of academic law students and staff looking for electronic legal information.
Makri, S.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Searching and reporting in Campbell Collaboration systematic reviews: A systematic assessment of current methods

open access: yesCampbell Systematic Reviews
The search methods used in systematic reviews provide the foundation for establishing the body of literature from which conclusions are drawn and recommendations made.
Sarah Young   +7 more
doaj   +1 more source

The Positive Effects of Self-Regulation Strategy in EFL Reading Dynamics

open access: yesJournal of English Language and Pedagogy
Amidst complex reading learning enterprises, it is fair to be acknowledged that globalized EFL learners need to improve their reading competencies and activate a self-regulation strategy to experience a positively sound reading learning atmosphere and ...
Kristian Florensio Wijaya
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

School library user studies

open access: yesKnjižnica: revija za področje bibliotekarstva in informacijske znanosti, 2014
AbstractThe analysis of the results of a questionnaire answered by Slovene primary and secondary school librarians is presented in the article. The purpose of the study was to determine if library user studies were being performed in our school libraries. It was confirmed that more studies had been conducted by school librarians with a completed higher
openaire   +2 more sources

Return on Instruction: Methods for Assessing the Impact of Information Literacy Instruction on the Use of Electronic Resources [PDF]

open access: yes, 2015
Moving from simplistic, open web search strategies sufficient for high school level work to independently navigating the complex system of information sources available on college campuses is a developmental milestone for undergraduate students.
Branch, Nicole A., McKeigue, Elizabeth
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy