We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
Evaluating machine learned nuclear data precision in full core nuclear reactor Monte Carlo neutronics and computational efficiency analyses. [PDF]
Hashemi A, Macián-Juan R, Ohlerich M.
europepmc +1 more source
Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul +8 more
wiley +1 more source
Scaffold-Based Libraries Versus Make-on-Demand Space: A Comparative Assessment of Chemical Content. [PDF]
Bui L +4 more
europepmc +1 more source
Library Manpower Requirements Studied
openaire +2 more sources
Metabolic Profiling of the EmDia Cohort by LC-MS Reveals Empagliflozin-Intake Associated Regulation of 1,5-anhydroglucitol and Urate. [PDF]
Schmitt F +7 more
europepmc +1 more source
Identification of novel DNA sequence motifs that modulate transcription in T cells. [PDF]
Knoetze N +4 more
europepmc +1 more source
Library-on-Library Intercellular Labeling for Selection of Biotin Ligase and Acceptor Peptides. [PDF]
Lakkanasirorat B +5 more
europepmc +1 more source
A droplet microfluidics-based platform for generating target-specific, natively-paired immune libraries and identifying potent and developable antibodies. [PDF]
Ramasubramanian A +24 more
europepmc +1 more source

