Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Citation Analisis as a Tool of Library Collections Evaluation
This paper discusses about citation analisis as a tool that can be used in performing library collection evaluation. The discussion include source, scope and analysis parameter, literature character, and the analysis advantage of citation.
Nurul Hayati
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Varying Student Behaviours Observed in the Library Prompt the Need for Further Research
Objective – To determine if the behaviours of students studying in the library are primarily study or non-study related, the extent to which these behaviours occur simultaneously, what types of study and non-study behaviours are most common, and if the ...
Maria Melssen
doaj +3 more sources
The benefits of applying Kahoot media in modern EFL teaching-learning contexts
It will be more reasonable for second language teachers to be more literate concerning the optimal internalization of proper technological learning platforms in their habitual classroom activities.
Kristian Florensio Wijaya
doaj +1 more source
Health effects of Indigenous language use and revitalization: a realist review
Background Indigenous populations across the world are more likely to suffer from poor health outcomes when compared to other racial and ethnic groups.
D. H. Whalen +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Escalating EFL Collaborative Writing Culture through the Use of Google Docs
Since EFL writing learning enterprises are frequently regarded as single-handedly activities, collaborative writing culture plays a crucial role in increasing globalized EFL learners’ writing motivation leading them to become more optimistic, innovative,
Kristian Florensio Wijaya
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Kajian Ergonomi Pada Display Statis (Penunjuk Informasi) di Perpustakaan Universitas Bina Darma
The purpose of this study to find out what forms of static displays (information pointers) are provided by the Bina Darma University Library which are then studied in terms of ergonomics based on the value of comfort, beauty, and usefulness. The type of
Aisyah Wahyu Kusuma Ningrum +1 more
doaj +1 more source

