Results 71 to 80 of about 4,573,689 (264)

The spatial patterning of emergency demand for police services: a scoping review

open access: yesCrime Science
This preregistered scoping review provides an account of studies which have examined the spatial patterning of emergency reactive police demand (ERPD) as measured by calls for service data.
Samuel Langton   +2 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

State promotion of local public goods: The case of public libraries, 1880-1929 [PDF]

open access: yes, 2016
The public library movement of the late nineteenth and early twentieth centuries led to a significant expansion of library services across the United States.
Kevane, Michael J, Sundstrom, William A.
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The Effect of Library Orientation on Library Knowledge

open access: yes, 2014
Previous research shows that the anxiety of not knowing how to use the library is a major factor in the decline in library attendance. In this study, the hypothesis was that the knowledge and attitude of students who participated in the library ...
Baca, Lilli-Anna
core   +1 more source

How Well Do Ontario Library Web Sites Meet New Accessibility Requirements? [PDF]

open access: yes, 2012
New changes to Ontario law will require library web sites to comply with the Web Content Accessibility Guidelines, version 2.0 (WCAG 2.0). This study evaluates 64 Ontario university, college, and public library web sites to see how well they comply with ...
Oud, Joanne
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Tales of health crises: Indonesia’s dynamic narratives and counter-narratives about pandemics

open access: yesCogent Arts & Humanities
This study explored Indonesia’s diverse narratives and counter-narratives concerning pandemics with a focus on public sentiment and governmental responses.
Rahmi Rahmi   +5 more
doaj   +1 more source

Hulk Smash”™ Busting the OAA Silo! [PDF]

open access: yes, 2015
This poster focuses on Lavery Library’s collaboration with the Office of Academic Affairs, OAA. At St. John Fisher College students with learning disabilities testing accommodations take their exams in the library instead of a testing center.
Celata, Stacy
core   +1 more source

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