Results 71 to 80 of about 4,623,855 (303)
The spatial patterning of emergency demand for police services: a scoping review
Crime ScienceThis preregistered scoping review provides an account of studies which have examined the spatial patterning of emergency reactive police demand (ERPD) as measured by calls for service data.
Samuel Langton +2 more
doaj +1 more source
State promotion of local public goods: The case of public libraries, 1880-1929 [PDF]
, 2016 The public library movement of the late nineteenth and early twentieth centuries led to a significant expansion of library services across the United States.
Kevane, Michael J, Sundstrom, William A.
core +1 more source
An Assessment of Education and Training Needs for Bibliographic Instruction Librarians [PDF]
, 1990 A study was conducted in 1986 by the Education and Library Use Committee of the Wisconsin Association of Academic Librarians to determine the educational backgrounds and characteristics of bibliographic instruction (BI) librarians in Wisconsin.
Mandernack, Scott
core +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Tales of health crises: Indonesia’s dynamic narratives and counter-narratives about pandemics
Cogent Arts & HumanitiesThis study explored Indonesia’s diverse narratives and counter-narratives concerning pandemics with a focus on public sentiment and governmental responses.
Rahmi Rahmi +5 more
doaj +1 more source
How Well Do Ontario Library Web Sites Meet New Accessibility Requirements? [PDF]
, 2012 New changes to Ontario law will require library web sites to comply with the Web Content Accessibility Guidelines, version 2.0 (WCAG 2.0). This study evaluates 64 Ontario university, college, and public library web sites to see how well they comply with ...
Oud, Joanne
core +3 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source