Results 81 to 90 of about 4,573,689 (264)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
New Functions for Libraries and Information Centers [PDF]
تحقیقات اطلاعرسانی و کتابخانههای عمومی, 2012 Purpose: In this article, the author critically discusses the defined functions which have been propounded for libraries till now. The most important of these functions are education and entertainment. Method: The present article is an opinion article in
Gholamreza Fadaie
doaj
A Study on the Open Source Digital Library Software's: Special Reference to DSpace, EPrints and Greenstone [PDF]
, 2012 The richness in knowledge has changed access methods for all stake holders in retrieving key knowledge and relevant information. This paper presents a study of three open source digital library management software used to assimilate and disseminate ...
Gul, Sumeer +3 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Padrões de citação dos estudantes de mestrado: estudo de caso de estudantes de Ciência da Informação
Páginas a&b, 2019 This study aimed to respond to the need of the FEUP Library to acquire knowledge about the citation patterns of its master’s students. In order to meet this need a methodology was developed and validated for a bibliometric study replicable in any program
Nuno Paiva Andrade +2 more
doaj +1 more source
Information Seeking in Library: Study of the Thingking of Michel Foucault [PDF]
, 2019 Users actually have their own power over information managed by libraries, to fulfill their own expectations of truth according to the perspective of the libraryitself.
Putra, P. (Purwnto)
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Library purchasing consortia: achieving value for money and shaping the emerging electronic marketplace [PDF]
, 1998 Drawing on a current study, funded by the British Library Research and Innovation Centre, the context of higher education libraries is discussed, including funding and costs and recent major official reports on education and libraries.
Ball, David, Pye, Jo
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source