PEP-EDIT: a web server for the 3D generation and interactive editing of complex peptides. [PDF]
Chevrollier N +7 more
europepmc +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Smart library personalized resource proactive recommendation system integrating user profiling and knowledge graphs. [PDF]
Xu F.
europepmc +1 more source
Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi +8 more
wiley +1 more source
Libraries as Spaces for Inclusive Communities: A Literature Review. [PDF]
Rodríguez Poveda SP +3 more
europepmc +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Multidimensional factors influencing continuance usage intention of university library self-service systems: An empirical analysis based on an extended TAM-UTAUT. [PDF]
Cao K, Wang P, Zhang C, Zhao J.
europepmc +1 more source
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Digital infrastructure to support and share daily high-throughput experimental materials research.
Mittmann LA +11 more
europepmc +1 more source
Pig Matrix: a matched multiomics 3D regulatory genomics database for evolutionary and comparative analyses in pigs. [PDF]
Guo C +20 more
europepmc +1 more source

