Results 41 to 50 of about 279,032 (254)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
License Plate Recognition Methods Employing Neural Networks
IEEE Access, 2023 Advances in both parallel processing capabilities because of graphical processing units (GPUs) and computer vision algorithms have led to the development of deep neural networks (DNN) and their utilization in real-world applications.
Muhammad Murtaza Khan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Detection Algorithm of Cascaded Adaboost License Plate Based on HSV color model and MB_LBP Features
四川大学学报. 自然科学版, 2018 License plate detection is an important part of the license plate recognition system, which deeply affects the accuracy of license plate recognition. A method for cascade adaboost license plate detection based on HSV color model and multi-block local ...
MA Yong-Jie, LI Huan, LIU Jiao-Jiao
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
ICTACT Journal on Image and Video Processing, 2018 License plate detection and recognition is the one of the major aspects of applying the image processing techniques towards intelligent transport systems.
V Baranidharan +3 more
doaj +1 more source
An All-in-One Vehicle Type and License Plate Recognition System Using YOLOv4
Sensors, 2022 In smart surveillance and urban mobility applications, camera-equipped embedded platforms with deep learning technology have demonstrated applicability and effectiveness in identifying various targets.
Se-Ho Park +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Efficient Scale-Adaptive License Plate Detection System [PDF]
IEEE Transactions on Intelligent Transportation Systems, 2019 License plate detection is a common problem in traffic surveillance applications. Although some solutions have been proposed in the literature, their success is usually restricted to very specific scenarios, with their performance dropping in more demanding conditions.
Miguel Molina-Moreno +2 more
openaire +2 more sources