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Lichen sclerosus is a progressive, inflammatory dermatosis characterized with porcelain white sclerotic plaques most commonly in the anogenital area of postmenopausal women. Children and men can also be affected. Extragenital involvement may occur.
Ergin, Şeniz
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Climacteric, 2021
Lichen sclerosus of the vulva (LSV) is seen frequently enough to warrant knowing how to diagnose it and institute appropriate treatment strategies. LSV is a chronic skin disorder, very likely of autoimmune origin, which may affect various areas of the perineum, although some women may be affected in extragenital areas.
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Lichen sclerosus of the vulva (LSV) is seen frequently enough to warrant knowing how to diagnose it and institute appropriate treatment strategies. LSV is a chronic skin disorder, very likely of autoimmune origin, which may affect various areas of the perineum, although some women may be affected in extragenital areas.
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Cytokine alterations in lichen sclerosus: an immunohistochemical study
BACKGROUND: Although the histology of lichen sclerosus is characteristic, the precise nature of the inflammatory changes and the signals provoking them is uncertain. OBJECTIVES: To delineate the inflammatory changes in lichen sclerosus more accurately by
P.R. Millard +9 more
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Dermatologic Clinics, 1992
Lichen sclerosus is a skin condition affecting all areas of the body at all ages and in both sexes. It appears to be a histologic and clinical entity, although in very many respects it is close to lichen planus and morphea. Its cause and pathogenesis are not established, but a link with autoimmune disease is recognized.
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Lichen sclerosus is a skin condition affecting all areas of the body at all ages and in both sexes. It appears to be a histologic and clinical entity, although in very many respects it is close to lichen planus and morphea. Its cause and pathogenesis are not established, but a link with autoimmune disease is recognized.
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JAMA Dermatology, 2022
This Patient Page describes the symptoms, diagnosis, and treatment of vulvar lichen sclerosus.
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This Patient Page describes the symptoms, diagnosis, and treatment of vulvar lichen sclerosus.
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Lichen sclerosus premenarche: autoimmunity and immunogenetics
Lichen sclerosus is among the most frequently seen paediatric vulval disorders. In adults a strong association between lichen sclerosus and autoimmune diseases, and also with HLA class II locus DQ7, has been well demonstrated in women and a weaker ...
Marren, P +4 more
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Australasian Journal of Dermatology, 1995
SUMMARYLichen sclerosus in childhood involves predominantly the genital area, often with purpura and erosions, which raises concerns of sexual abuse. Potent topical corticosteroids give a good clinical response over several months, although maintenance with weaker formulations is usually required. The long‐term prognosis remains uncertain.
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SUMMARYLichen sclerosus in childhood involves predominantly the genital area, often with purpura and erosions, which raises concerns of sexual abuse. Potent topical corticosteroids give a good clinical response over several months, although maintenance with weaker formulations is usually required. The long‐term prognosis remains uncertain.
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An Assessment of Vulval Lichen Sclerosus
Australian and New Zealand Journal of Obstetrics and Gynaecology, 1978Summary: Vulval lichen sclerosus (L.S.) has been assessed clinically, colposcopically, and histologically to ascertain the suitability of including this condition in the nomenclature proposed by the International Society for the Study of Vulval Disease (I.S.S.V.D.).In many cases the macroscopic appearance of lichen sclerosus is characteristic, but ...
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Journal of Obstetrics and Gynaecology Canada, 2010
Michael, Shier, Sirine, El-Khatib
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Michael, Shier, Sirine, El-Khatib
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