Results 21 to 30 of about 51 (49)

Investigating the Modulation of Corticomotor and Neuromuscular Function by Contralateral and Ipsilateral Experimental Pain Applied During Cycling

Scandinavian Journal of Medicine &Science in Sports, Volume 35, Issue 9, September 2025.
ABSTRACT Pain can impair exercise performance, but its influence on motor control, in particular the effect of robust experimental pain on the timecourse of corticomotor responses throughout prolonged, exhaustive cycling, remains unclear. We tested the hypothesis that an augmented experimental pain intervention applied to exercising and non‐exercising ...
Jenny Zhang, Niloofar Honarvar, Arezou Habibirad, Kirsty Bannister, Martin J. MacInnis, Saied Jalal Aboodarda   +5 more
wiley   +1 more source

Effects of a Single Session 400 Hz Transcranial Pulsed Current Stimulation on Corticospinal and Corticocortical Excitability and Hand Dexterity: A Double‐Blind RCT

Psychophysiology, Volume 62, Issue 7, July 2025.
ABSTRACT The effects of 400 Hz anodal and cathodal transcranial pulsed current stimulation of the primary motor cortex (400 Hz a‐tPCSM1, 400 Hz c‐tPCSM1) on corticospinal excitability (CSE) and corticocortical excitability (CCE) and hand dexterity remain underexplored.
Shapour Jaberzadeh, Mona Malekahmad, Renming Liu, Maryam Zoghi   +3 more
wiley   +1 more source

Investigating the Effects of Anodal Transcranial Pulsed Current Stimulation at Low Frequencies (0.5 to 5 Hz) on Corticospinal and Corticocortical Excitability

Psychophysiology, Volume 62, Issue 6, June 2025.
ABSTRACT The mechanism underlying transcranial pulsed current stimulation (tPCS) as a non‐invasive neuromodulation technique has garnered considerable attention in recent years. However, the effects of anodal tPCS (a‐tPCS) at low frequencies remain unexplored.
Mona Malekahmad, Ashlyn Frazer, Maryam Zoghi, Shapour Jaberzadeh   +3 more
wiley   +1 more source

TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine‐1‐Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects

Clinical Pharmacology &Therapeutics, Volume 117, Issue 3, Page 787-797, March 2025.
Current anti‐epileptic drugs lack efficacy, cause many side effects and one third of all patients are treatment‐resistant. Drugs targeting the sphingosine‐1‐phosphate receptor show potential anti‐convulsant effects in animal models and decrease cortical excitability in patients with multiple sclerosis, but available compounds alter lymphocyte ...
Catherine M. K. E. de Cuba, Annika A. de Goede, Erica S. Klaassen, Marije E. Otto, Robert J. Doll, Jessica Kim, Mark A. Demitrack, Ruihua Chen, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +9 more
wiley   +1 more source

Fluoxetine does not influence response to continuous theta burst stimulation in human motor cortex

Neuropsychopharmacology Reports, Volume 45, Issue 1, March 2025.
cTBS can produce both inhibition and paradoxical facilitation of cortical MEPs. Contrary to the impact of other SSRIs on alternative forms of non‐invasive brain stimulation, fluoxetine 20 mg did not modulate the effect of cTBS. Abstract Aim Selective serotonin reuptake inhibitors are thought to exert a clinical effect through various mechanisms ...
Duncan K. Austin, Lourenço M. D. Amador, Lucia M. Li, Simon J. Little, John C. Rothwell   +4 more
wiley   +1 more source

Clinical efficacy of low‐dose Perampanel correlates with neurophysiological changes in familial adult myoclonus epilepsy 2

Epilepsia Open, Volume 10, Issue 1, Page 321-328, February 2025.
Abstract Familial adult myoclonus epilepsy (FAME) management relies on antiseizure medications (ASMs), which inadequately address myoclonus and cortical tremor. This study evaluates Perampanel (PER), an AMPA‐receptor antagonist, for treating FAME symptoms. Fifteen FAME2 patients participated in an observational prospective study.
Antonietta Coppola, Claudia Cuccurullo, Gianmaria Senerchia, Marica Rubino, Liana Veneziano, Francesco Brancati, Luigi Baratto, Valentina Virginia Iuzzolino, Leonilda Bilo, Pasquale Striano, Raffaele Dubbioso   +10 more
wiley   +1 more source

Corticomotor pathway function and recovery after stroke: a look back and a way forward

The Journal of Physiology, Volume 603, Issue 3, Page 651-662, 1 February 2025.
Abstract figure legend Monohemispheric stroke damages cortical neurons, resulting in cell death or demyelination. Consequently, descending output is desynchronized, and motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) can be small and polyphasic.
Maxine J. Shanks, Winston D. Byblow
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation modifies cortical excitability in middle‐aged and older adults

Psychophysiology, Volume 62, Issue 1, January 2025.
Abstract There is a growing interest in the clinical application of transcutaneous auricular vagus nerve stimulation (taVNS). However, its effect on cortical excitability, and whether this is modulated by stimulation duration, remains unclear. We evaluated whether taVNS can modify excitability in the primary motor cortex (M1) in middle‐aged and older ...
Ashraf N. H. Gerges, Lynton Graetz, Susan Hillier, Jeric Uy, Taya Hamilton, George Opie, Ann‐Maree Vallence, Felicity A. Braithwaite, Saran Chamberlain, Brenton Hordacre   +9 more
wiley   +1 more source

Short‐latency afferent inhibition is reduced with cold‐water immersion of a limb and remains reduced after removal from the cold stimulus

Experimental Physiology, Volume 109, Issue 11, Page 1817-1825, 1 November 2024.
Abstract The experience of pain that is induced by extremely cold temperatures can exert a modulatory effect on motor cortex circuitry. Although it is known that immersion of a single limb in very cold water can increase corticomotor excitability it is unknown how afferent input to the cortex shapes excitatory and inhibitory processes.
Eden T. Delahunty, Leanne M. Bisset, Justin J. Kavanagh   +2 more
wiley   +1 more source

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Cryptanalyzing an image cipher using multiple chaos and DNA operations

Journal of King Saud University - Computer and Information Sciences, 2023
Heping Wen
exaly