Results 41 to 50 of about 770,641 (335)

MHD mixed convection and entropy generation of nanofluid in a lid-driven U-shaped cavity with internal heat and partial slip

The Physics of Fluids, 2019
This contribution simulates the impact of partial slip on entropy generation due to magnetohydrodynamic, mixed convection of nanofluids in a lid-driven U-shaped cavity with discrete heating.
A. Rashad, M. Mansour, T. Armaghani, Ali J. Chamkha   +3 more
semanticscholar   +1 more source

The habitability of a stagnant-lid Earth [PDF]

, 2017
Context. Plate tectonics is considered a fundamental component for the habitability of the Earth. Yet whether it is a recurrent feature of terrestrial bodies orbiting other stars or unique to the Earth is unknown.
Nicola Tosi, Nicola Tosi, M. Godolt, M. Godolt, B. Stracke, T. Ruedas, J. Grenfell, D. Höning, A. Nikolaou, A. Nikolaou, A. Plesa, D. Breuer, T. Spohn   +12 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Comprehensive Performance Evaluation System Based on Environmental and Economic Benefits for Optimal Allocation of LID Facilities

Water, 2019
In recent years, urban flooding occurred frequently because of extreme rainstorms. Sponge city construction can effectively mitigate urban flooding and improve urban rainwater utilization.
Yiran Bai, Yuhong Li, Ruoyu Zhang, Na Zhao, X. Zeng   +4 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Distinct Cytokine Profiles Correlate with Disease Severity and Outcome in Longitudinal Studies of Acute Hepatitis B Virus and Hepatitis D Virus Infection in Chimpanzees

mBio, 2020
Historical studies conducted in chimpanzees gave us the opportunity to investigate the basis for the different severities of liver damage and disease outcome associated with infection with wild-type hepatitis B virus (HBV) versus a precore HBV mutant ...
Ronald E. Engle, Davide De Battista, Emily J. Danoff, Hanh Nguyen, Zhaochun Chen, Paolo Lusso, Robert H. Purcell, Patrizia Farci   +7 more
doaj   +1 more source

Ambivalent effects of added layers on steady kinematic dynamos in cylindrical geometry: application to the VKS experiment

, 2005
The intention of the ''von Karman sodium'' (VKS) experiment is to study the hydromagnetic dynamo effect in a highly turbulent and unconstrained flow. Much effort has been devoted to the optimization of the mean flow and the lateral boundary conditions in
Chiffaudel, A., Daviaud, F., Gerbeth, G., Léorat, J., Ravelet, F., Stefani, F., Xu, M.   +6 more
core   +3 more sources

A centrifugo-magnetically actuated gas micropump [PDF]

, 2006
This paper describes a novel gas micropump on a centrifugal microfluidic platform. The pump is integrated on a passive and microstructured polymer disk which is sealed with an elastomer lid featuring paramagnetic inlays.
Ducrée, Jens, Haeberle, S., Schmitt, N., Zengerle, Roland   +3 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source