Prevention of pain during injection of microemulsion propofol: application of lidocaine mixture and the optimal dose of lidocaine [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundSimilar to lipid emulsion propofol, microemulsion propofol also causes a high incidence of pain during intravenous injection. Various methods have been used to minimize the incidence and severity of pain on injection of lipid emulsion propofol.
Hyun-Sik Kim +9 more
doaj +1 more source
Gabapentin for pain management after osmotic dilator insertion and prior to dilation and evacuation: A randomized controlled trial. [PDF]
, 2020 ObjectiveTo evaluate if gabapentin 600 mg reduces pain after osmotic dilator placement the day before a dilation and evacuation (D&E) procedure.Study designWe conducted a double-blind, placebo-controlled, randomized (stratified by vaginal parity ...
Chen, Melissa J +5 more
core +3 more sources
Advanced Science, EarlyView.Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang +25 more
wiley +1 more source
The challenge of evaluating pain and a pre-incisional local anesthetic block. [PDF]
, 2014 Background. Our objective was to test the effectiveness of a local anesthetic line block administered before surgery in reducing postoperative pain scores in dogs undergoing ovariohysterectomy (OVHX). Methods.
Kass, Philip H +3 more
core +2 more sources
Anticancer Research, 2018 Background/Aim: Mortality from breast cancer is usually attributable to metastasis. In vitro data suggest that amide local anaesthetics, e.g. lidocaine, inhibit metastasis by multiple mechanisms and recent in vivo data support this.
J. Freeman +6 more
semanticscholar +1 more source
Translation of a Human‐Based Malaria‐on‐a‐Chip Phenotypic Disease Model for In Vivo Applications
Advanced Science, EarlyView.Inoculation of the Malaria‐on‐a‐Chip model with human erythrocytes infected with Plasmodium falciparum can support the entire intraerythrocytic lifecycle for 7 days in vitro. Utilizing this human‐based, serum‐free model provides an alternative to animal testing by introducing a human‐based, preclinical alternative for antimalarial therapeutic delivery.
Michael J. Rupar +15 more
wiley +1 more source
Intracuff lidocaine 2% for prevention of postoperative cough and sore throat
Al-Azhar Assiut Medical Journal, 2018 Background Tracheal intubation results in an alteration of the laryngeal mucosa. Coughing during emergence from general anesthesia is a common clinical problem.
Mokhtar Mahmoud Younes
doaj +1 more source
Rocuronium-induced withdrawal movement: influence of ketorolac or a combination of lidocaine and ketorolac pretreatment [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundPain on injection of rocuronium is a common clinical problem. We compared the efficacy of lidocaine, ketorolac, and the 2 in combination as pretreatment for the prevention of rocuronium-induced withdrawal movement.MethodsFor this prospective ...
Younghoon Jeon +5 more
doaj +1 more source
Lidocaine effects on acetylcholine-elicited currents from mouse superior cervical ganglion neurons [PDF]
, 2013 Lidocaine is a commonly used local anaesthetic that, besides blocking voltage-dependent Na+ channels, has multiple inhibitory effects on muscle-type nicotinic acetylcholine (ACh) receptors (nAChRs).
Alberola-Die, Armando +3 more
core +2 more sources
Lidocaine Infusion: A Promising Therapeutic Approach for Chronic Pain
Journal of Anesthesia & Clinical Research, 2017 Opioid abuse is a national epidemic in the United States, where it is estimated that a prescription drug overdose death occurs every 19 minutes. While opioids are highly effective in acute and subacute pain control, their use for treatment of chronic ...
Enas S Kandil +2 more
semanticscholar +1 more source