Results 151 to 160 of about 22,466 (245)

Transoral Ultrasound in the Diagnostic Workup of Peritonsillar Abscess—A Randomized Clinical Trial

The Laryngoscope, EarlyView.
Peritonsillar abscess frequently mimics peritonsillar cellulitis, exposing many patients to unnecessary and often painful blind needle aspirations. In this multicenter randomized clinical trial of 95 patients, adding transoral ultrasound to standard examination reduced needle aspiration attempts by nearly one third.
Tobias Todsen, Mads G. Stage, Jacob Melchiors, Mathias Mejdahl, Amalie P. Posselt, Anders R. Madsen, Christoffer H. Hahn, Christian Godballe, Sanne H. Michaelsen   +8 more
wiley   +1 more source

Effects of Ferrostatin‐1 on Vocal Folds in Aging Rats

The Laryngoscope, EarlyView.
Age‐related vocal fold degeneration is associated with oxidative stress, and ferroptosis may contribute to structural changes in aging vocal folds. In this aged rat model, intracordal injection of the antioxidant ferrostatin‐1 attenuated ferroptosis‐related changes and was associated with modulation of collagen accumulation, hyaluronic acid ...
Yong‐Il Cheon, Soo‐Young Bang, Ji Min Kim, Ha‐Nee Kwon, Minhyung Lee, Eui‐Suk Sung, Jin‐Choon Lee, Byung‐Joo Lee, Sung‐Chan Shin   +8 more
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

The Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen, Carmen Esna, Camille Prigent, Anna Miles   +3 more
wiley   +1 more source

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

The Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar, Eric Allen, Yun‐Lun Liu, Alexandra D. D'Oto, Rishi Suresh, Adrianna Shembel, Ted Mau   +6 more
wiley   +1 more source

Evaluating the Local Response of a Novel Injectable Capsule for Drug Delivery in the Trachea

The Laryngoscope, EarlyView.
A novel PLGA polymer capsule was developed for localized pretracheal drug delivery and evaluated for short‐term local tissue safety in a rabbit model. Implant placement was confirmed by ultrasound and was well tolerated over 14 days, with preservation of airway patency, native tracheal architecture, and biomechanical properties.
Denzel Ryan D. Cruz, Nour Awad, Nicholas Russell, Juliana El Sheikh, Logan Obermeyer, Peter J. Larson, Yoonjee C. Park, Gregory R. Dion   +7 more
wiley   +1 more source

Intraoperative Bradycardia: Evaluating Vasovagal Events in Adult Suspension Microlaryngeal Surgery

The Laryngoscope, EarlyView.
This retrospective single‐surgeon cohort study of 190 adults undergoing suspension microlaryngoscopy found that 8.9% (17/190) developed significant intraoperative bradycardia consistent with a vasovagal response (VVR). No demographic, comorbidity, or procedural factors were significantly associated with VVR, though most affected patients required ...
Thomas Q. McClelland, Cyrus W. Abrahamson, Abbey L. Landini, Andrew P. Stein, James A. Burns   +4 more
wiley   +1 more source

Invention of the Flexible Fiberoptic Nasopharyngolaryngoscope: Perspectives From the East

The Laryngoscope, EarlyView.
The fiberoptic nasopharyngolaryngoscope was developed in 1967 by Drs. Masayuki Sawashima, Hajime Hirose, and Osamu Fujimura at the University of Tokyo's Research Institute of Logopedics and Phoniatrics (RILP), building on Dr. Shigeto Ikeda's 1962 fiberoptic bronchoscope during Japan's postwar surge in technological innovation.
Carolyn J. Khoury, Rumi Ueha, Tyler G. Chan, Katherine Tai, Peak Woo, Hiroshi Imagawa, Kenji Kondo, Anaïs Rameau   +7 more
wiley   +1 more source

Vaginal Laser Treatment for Genitourinary Syndrome of the Menopause: A Dose‐Determining Study in Breast Cancer Survivors

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Breast cancer survivors (BCSs) receiving endocrine therapy frequently develop genitourinary syndrome of menopause, characterized by vaginal dryness, pain, and urinary symptoms. Fractional CO2 vaginal laser therapy has been proposed as a non‐hormonal management option, but the optimal number of treatment sessions remains unclear.
Sine Jacobsen, Marianne Glavind‐Kristensen, Anders Bonde Jensen, Axel Forman, Vibe Munk Bertelsen, Pinar Bor   +5 more
wiley   +1 more source

Stroke Following Facial Laser Resurfacing Procedure—A Case Report

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To describe the first reported case of embolic stroke with hemorrhagic conversion following a dermatologic energy‐based device procedure, highlighting its mechanism and clinical implications. Methods A detailed case review was conducted, including clinical presentation, imaging, and subsequent diagnostic workup. The patient provided
Tal Levy, Joel L. Cohen
wiley   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source