Results 181 to 190 of about 22,466 (245)
BJU International, EarlyView.Objectives To evaluate if bladder washing cytology (BWC) provides a diagnostic benefit in the initial evaluation of patients with neuro‐urological disorders. Patients and Methods This prospective cross‐sectional study investigated a consecutive series of patients with lower urinary tract symptoms referred for neuro‐urological evaluation at our ...
Fabienne Lehner +8 more
wiley +1 more source
First‐in‐human outpatient management of recurrent NMIBC with the Multi4 instrument
BJU International, EarlyView.Objectives To evaluate the feasibility, safety and diagnostic performance of outpatient management of recurrent non‐muscle‐invasive bladder cancer (NMIBC) under local anaesthesia using the Multi4 instrument, a series of preclinical studies were performed followed by a first‐in‐human clinical investigation.
Miden Melle‐Hannah +4 more
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Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley +1 more source
Effect of lidocaine and methyl lidocaine on cardiac conduction.
The Journal of Pharmacology and Experimental Therapeutics, 1977 The effects of lidocaine and methyl lidocaine on cardiac conduction were studied using His bundle recordings from isolated blood perfused dog hearts. The input and output characteristic of the atrioventricular (AV) node can be described as consisting of three components, namely, minimal conduction time, fatigue, and the effect of prematurity (deltaCT).
Man, RYK, Dresel, PE
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Annals of Emergency Medicine, 1980
Lidocaine is recognized as a first line drug for ventricular arrhythmias and has recently been used in acute myocardial infarction as prophylaxis against ventricular fibrillation. A 68-year-old man was erroneously given 2 gm of lidocaine by intravenous push and sustained a cardiac arrest. He was treated supportively and had complete recovery.
D L, Brown, J J, Skiendzielewski
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Lidocaine is recognized as a first line drug for ventricular arrhythmias and has recently been used in acute myocardial infarction as prophylaxis against ventricular fibrillation. A 68-year-old man was erroneously given 2 gm of lidocaine by intravenous push and sustained a cardiac arrest. He was treated supportively and had complete recovery.
D L, Brown, J J, Skiendzielewski
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Annals of Internal Medicine, 1983
Excerpt To the editor: Knapp and associates (1) indicate Cimetidine causes lidocaine serum concentrations to rise 75% in patients receiving a lidocaine infusion.
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Excerpt To the editor: Knapp and associates (1) indicate Cimetidine causes lidocaine serum concentrations to rise 75% in patients receiving a lidocaine infusion.
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Anesthesiology, 1982
Arterial lidocaine concentrations and the duration of motor anesthesia following the subarachnoid injection of 30 or 40 mg of lidocaine with or without epinephrine 0.3 mg were measured in 10 sedated dogs. As the dogs were sedated with ketamine, the duration of sensory anesthesia was not evaluated.
Ram S. Ravindran +3 more
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Arterial lidocaine concentrations and the duration of motor anesthesia following the subarachnoid injection of 30 or 40 mg of lidocaine with or without epinephrine 0.3 mg were measured in 10 sedated dogs. As the dogs were sedated with ketamine, the duration of sensory anesthesia was not evaluated.
Ram S. Ravindran +3 more
openaire +1 more source
Fentanyl and Lidocaine versus Lidocaine for Bier Block
Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control, 1992Background and Objectives. The present study was designed to assess the efficacy of fentanyl combined with dilute lidocaine solution for intravenous regional anesthesia of the arm. Methods. In ten volunteers, the nondominant arm was exposed to three
J M, Arthur +3 more
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