Cochrane Database of Systematic Reviews, 2018 BACKGROUND The management of postoperative pain and recovery is still unsatisfactory in a number of cases in clinical practice. Opioids used for postoperative analgesia are frequently associated with adverse effects, including nausea and constipation ...
S. Weibel +9 more
semanticscholar +1 more source
Emerging pharmacotherapy of tinnitus [PDF]
, 2009 Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen +43 more
core +1 more source
Development and Field Validation of Lidocaine-Loaded Castration Bands for Bovine Pain Mitigation
Animals, 2020 Castration is among the most common management procedures performed in the dairy and beef cattle industries and is mainly performed by surgery or elastic banding.
James W. Saville +11 more
doaj +1 more source
Effect of two-week continuous epidural administration of 2% lidocaine on mechanical allodynia induced by spinal nerve ligation in rats [PDF]
Anesthesia and Pain Medicine, 2020 Background Lidocaine is an effective against certain types of neuropathic pain. This study aimed to investigate whether timing of initiating continuous epidural infusion of lidocaine affected the glial activation and development of neuropathic pain ...
Yuseon Cheong +3 more
doaj +1 more source
Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]
, 2017 Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
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Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]
, 2018 ● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa +4 more
core +2 more sources
Journal of Pain Research, 2021 Jeffrey Gudin,1,2 Lynn R Webster,3 Emileigh Greuber,4 Kip Vought,4 Kalpana Patel,4 Louis Kuritzky5 1Department of Anesthesiology, Rutgers New Jersey Medical School, Newark, NJ, USA; 2Department of Anesthesiology and Pain Management, Englewood Hospital ...
Gudin J +5 more
doaj
Capsazepine prolongation of the duration of lidocaine block of sensory transmission in mice may be mediated by modulation of HCN channel currents [PDF]
PeerJ, 2019 Background and objectives Hyperpolarization-activation cyclic nucleotide-gated (HCN) channels contribute to the effects of lidocaine. Capsazepine (CPZ), a competitive inhibitor of capsaicin of transient receptor potential vanilloid-1 channel, has also ...
Wenling Zhao +7 more
doaj +2 more sources
New patents on topical anesthetics. [PDF]
, 2014 Anesthesia is defined as a total or partial loss of sensation and it may be general, local or topical, depending on the method of drug administration and area of the body affected.
CALVIERI, Stefano +6 more
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Lidocaine inhibits osteogenic differentiation of human dental pulp stem cells
Journal of International Medical Research, 2023 Objective Lidocaine is an amide local anaesthetic commonly used for pain control, however, few studies have investigated the effect of lidocaine on the osteogenic differentiation of human dental pulp stem cells (HDPSCs).
Eun-Jung Kim +6 more
doaj +1 more source