Results 21 to 30 of about 22,466 (245)

Capsazepine prolongation of the duration of lidocaine block of sensory transmission in mice may be mediated by modulation of HCN channel currents [PDF]

open access: yesPeerJ, 2019
Background and objectives Hyperpolarization-activation cyclic nucleotide-gated (HCN) channels contribute to the effects of lidocaine. Capsazepine (CPZ), a competitive inhibitor of capsaicin of transient receptor potential vanilloid-1 channel, has also ...
Wenling Zhao   +7 more
doaj   +2 more sources

Effect of epinephrine on the absorption of lidocaine following application to the oral mucosa in rats

open access: yesBMC Oral Health, 2021
Background We investigated the role of epinephrine in prolonging the localization of lidocaine on the oral mucosa and inhibiting its absorption in the blood of rats. Methods We used 7–8-week-old pathogen-free Wistar male rats (n = 128) for our study.
Rui Sasaki, Katsuhisa Sunada
doaj   +1 more source

Comparative study between benzydamine hydrochloride gel, lidocaine 5% gel and lidocaine 10% spray on endotracheal tube cuff as regards postoperative sore throat

open access: yesRevista Brasileira de Anestesiologia, 2016
Postoperative sore throat is a common complication after endotracheal intubation. After tracheal intubation, the incidence of sore throat varies from 14.4% to 50%.
Nashwa Abdallah Mekhemar   +3 more
doaj   +1 more source

Comparison of Lidocaine-Distilled Water and Lidocaine-Mgso4 Mixture in Epidural Anesthesia of Dog [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2006
Objective- To compare the lidocaine-MgSO4 combination with lidocaine-Distilled water inthe epidural of indigenous awake dogs.Design- Prospective experimental study.Animals- Five young (12±2 months) female indigenous dogs weighting (10.74 ± 0.44 kg ...
Seifollah Dehghani, Amin Bigham Sadegh
doaj  

Caudal Epidural Analgesia using Lidocaine alone and in Combination with Tramadol in Dromedary Camels [PDF]

open access: yesIranian Journal of Veterinary Surgery, 2014
Objective- This study was performed to investigate the analgesic effects of lidocaine and lidocaine/tramadol combination in epidural anaesthesia in dromedary camels.
Omid Azari   +2 more
doaj  

Evaluation and Comparison of the Effects of Intravenous Lidocaine versus Alkalinized Intracuff Lidocaine on Coughing and Postoperative Sore Throat

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Background: Coughing and sore throat are among the most common complications of intubation. Variety of drugs have been experimented to reduce these complications, but the information in this regard is limited and controversial. The current study compared
Mohamad Reza Safavi   +2 more
doaj   +1 more source

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi   +2 more
wiley   +1 more source

Intravenous lidocaine for the treatment of acute pain in the emergency department [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2016
Objective To evaluate intravenous lidocaine’s safety and efficacy as an analgesic agent in the treatment of a variety of painful conditions presenting to the emergency department.
Brendan Michael Fitzpatrick   +1 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

open access: yesAdvanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou   +6 more
wiley   +1 more source

Serum lidocaine concentration after epidural administration in dogs

open access: yesVeterinární Medicína, 2006
The pharmacokinetics of lidocaine deals with the measurement of lidocaine concentration in the blood and its changes over time. The toxicity of lidocaine is a function of its peak plasma concentration, which in turn depends on several factors including ...
D. Vnuk   +5 more
doaj   +1 more source

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