Results 61 to 70 of about 79,534 (262)

Nerve Impulse Conduction During Intravenous Lidocaine Injection [PDF]

, 1968
Rudolph H. de Jong, Roger A. Nace
openalex   +1 more source

A New Way to Use Hydrophobic Deep Eutectic Solvents: Improved Lead Detection Using an Ion‐Selective Electrode with a Polymer Membrane Modified by them

ChemPhysChem, EarlyView.
First use of hydrophobic deep eutectic solvents (HDESs) in the preparation of polymeric membrane lead‐sensitive ion‐selective electrodes is presented. It is found that enrichment of the membrane with HDES additive improves the electrode's parameters, primarily lowering the detection limit and increasing selectivity.
Cecylia Wardak, Malgorzata Grabarczyk, Mersiha Suljkanović, Jasmin Suljagić, Magdalena Wardak   +4 more
wiley   +1 more source

Profiling a Neo‐Antigen‐Driven Immune Response in Healthy Volunteers: A Randomized, Double‐Blind, Placebo‐Controlled Study of the KLH Challenge Model

Clinical Pharmacology &Therapeutics, EarlyView.
Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner, Hendrika W. Grievink, Mahdi Saghari, Michelle Osse, Thierry P.P. van den Bosch, Jeffrey Damman, Marieke L. de Kam, Jacobus Burggraaf, Naomi B. Klarenbeek, Manon A. A. Jansen, Matthijs Moerland   +10 more
wiley   +1 more source

Transmission of lidocaine hydrochloride across the placenta during caesarian section [PDF]

, 1969
Gordon Fox, Germain L. Houle
openalex   +1 more source

Success of Pilot Grant Program leads to Funding by Robert Saligman Charitable Foundation [PDF]

, 2017
In 2016, the Department of Surgery launched the Support of Surgery Research Activities Pilot Grant Program. In the first year alone, six projects were approved and funded.

core   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang, Viktoria Lahmann, Jan Philipp Bittner, Pablo Domínguez de María, Sven Jakobtorweihen, Irina Smirnova, Selin Kara   +6 more
wiley   +1 more source

A Three-dimensional Printed Low-cost Anterior Shoulder Dislocation Model for Ultrasound-guided Injection Training. [PDF]

, 2018
Anterior shoulder dislocations are the most common, large joint dislocations that present to the emergency department (ED). Numerous studies support the use of intraarticular local anesthetic injections for the safe, effective, and time-saving reduction ...
Au, Arthur K., Goodsell, Kelly, Ku, Bon, Lewiss, Resa E., Magee, Mark A., Mazza, Jacob M., Pugliese, Robert S., Risler, Zachary   +7 more
core   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

The Kinetics of Transfer of Lidocaine (Xylocaine®) across the Human Placenta [PDF]

, 1968
Sol M. Shnider, E. Leong Way
openalex   +1 more source

Management of paediatric procedure-related cancer pain

, 1999
Paediatric malignancy is not always painful in its own right; however, young patients with cancer undergo numerous painful procedures for diagnosis, therapy and supportive care, including lumbar puncture, bone marrow aspiration and biopsy.
Liossi, C.
core   +1 more source