Results 41 to 50 of about 127,431 (247)

Your lies don't leave me cold: Assessing direct, indirect and physiological measures of lie detection

open access: yesActa Psychologica
People tend to be bad at detecting lies: When explicitly asked to infer whether others tell a lie or the truth, people often do not perform better than chance.
Rima-Maria Rahal   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A Review on Artificial Intelligence methods and Signal Processing for EEG-Based lie and Truth Identification

open access: yesAl-Iraqia Journal for Scientific Engineering Research
 A false statement made with the goal of tricking someone is called a lie. Given how little there is to separate a falsehood from the truth, it can be difficult to tell the two apart.
Hamza Waleed Hamza, Ammar A. Al-Hamadani
doaj   +1 more source

Can a Robot Catch You Lying? A Machine Learning System to Detect Lies During Interactions

open access: yesFrontiers in Robotics and AI, 2019
Deception is a complex social skill present in human interactions. Many social professions such as teachers, therapists and law enforcement officers leverage on deception detection techniques to support their work activities.
Jonas Gonzalez-Billandon   +10 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Event-Related Potentials in Deception Detection [PDF]

open access: yesPsychology in Russia: State of Art, 2011
The problem of lie detection has a long history. Main achievements in this field are concerned with registration of peripheral nervous system indicators.
Evgenij S. Isaychev   +3 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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