Results 21 to 30 of about 21,386 (201)

Quantum geometric machine learning for quantum circuits and control

New Journal of Physics, 2020
The application of machine learning techniques to solve problems in quantum control together with established geometric methods for solving optimisation problems leads naturally to an exploration of how machine learning approaches can be used to enhance ...
Elija Perrier, Dacheng Tao, Chris Ferrie
doaj   +1 more source

Labanotation Generation From Motion Capture Data for Protection of Folk Dance

IEEE Access, 2020
Labanotation is one of the well-known notation systems for the documenting and archiving of human motion. It plays a powerful role in dance protection, choreography analysis, and so on.
Jiaji Wang, Zhenjiang Miao, Ningwei Xie, Wanru Xu, Ang Li   +4 more
doaj   +1 more source

Accelerated discovery of machine-learned symmetries: Deriving the exceptional Lie groups , And

Physics Letters, 2023
Recent work has applied supervised deep learning to derive continuous symmetry transformations that preserve the data labels and to obtain the corresponding algebras of symmetry generators. This letter introduces two improved algorithms that significantly speed up the discovery of these symmetry transformations.
Forestano, Roy T., Matchev, Konstantin T., Matcheva, Katia, Roman, Alexander, Unlu, Eyup B., Verner, Sarunas   +5 more
openaire  

Data Obfuscation for Privacy-Preserving Machine Learning Using Quantum Symmetry Properties

Big Data and Cognitive Computing
This study introduces a data obfuscation technique that leverages the exponential map of Lie-group generators. Originating from quantum machine learning frameworks, the method injects controlled noise into these generators, deliberately breaking symmetry
Sebastian Raubitzek, Sebastian Schrittwieser, Alexander Schatten, Kevin Mallinger   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source