Results 71 to 80 of about 65,367 (292)

German tradition heritage in Guimarães Rosa's literature

open access: yesPandaemonium Germanicum: Revista de Estudos Germanísticos, 2011
Die Nähe zwischen Musik, Philosophie und Literatur in der deutschen Tradition und in ihren Methoden faszinierte João Guimarães Rosa zutiefst. Aus dem deutschen Beispiel heraus entwickelte er seine Methodenlehre der Organisation der brasilianischen ...
Ivan Cláudio Pereira Siqueira
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Interacting with Annotated and Synchronized Music Corpora on the Dezrann Web Platform

open access: yesTransactions of the International Society for Music Information Retrieval
Open datasets with annotated corpora are crucial to foster research in music information retrieval (MIR) studies and to disseminate knowledge towards musicians and the general public.
Charles Ballester   +25 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Apie laisvę, karą ir dainas. Über Freiheit, Krieg und Lieder [PDF]

open access: yesLiteratūra (Vilnius), 2009
Der Professor Donatas Sauka in der im Jahr 1970 er­schienenen Monographie Die Eigentümlichkeit und Wert der Volksdichtung analysierte die alten litau­ischen Lieder des Krieges.
Darius Kuolys
doaj  

Soloists of ALEA III, December 12, 1989 [PDF]

open access: yes, 1989
This is the concert program of Soloists of ALEA III performance on Tuesday, December 12, 1989 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Two-photon-excited fluorescence (TPEF) and fluorescence lifetime imaging (FLIM) with sub-nanosecond pulses and a high analog bandwidth signal detection

open access: yes, 2017
Two-photon excited fluorescence (TPEF) microscopy and fluorescence lifetime imaging (FLIM) are powerful imaging techniques in bio-molecular science. The need for elaborate light sources for TPEF and speed limitations for FLIM, however, hinder an even ...
Eibl, Matthias   +4 more
core   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

Mozart and l'impresario

open access: yes, 2006
In May 1856, less than a year after opening, Jacques Offenbach’s Théâtre des Bouffes-Parisiens mounted a production of Mozart’s Der Schauspieldirektor entitled L’Impresario.
Everist, Mark
core  

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