Results 161 to 170 of about 321,803 (309)

Imaginaire et lien social

open access: yesCalenda, 2009
C'est parfois plus violemment et plus distinctement que le monde s'offre à nous, contournant les outils d'intellectualisation et les baromètres, tordant les mesures et les chiffres, plus qu'à l'accoutumée. Ainsi se déploient les manifestations de ce qui tient la société, de ce qui fait d'elle un corps, collectif mais ténu, et nous rappelle combien les ...
openaire   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

open access: yesAdvanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang   +10 more
wiley   +1 more source

Socialiser la foi. Une esquisse de parcours ecclésial

open access: yesBulletin du Centre d’Études Médiévales d’Auxerre, 2013
Dominique Iogna-Prat
doaj   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

open access: yesAdvanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li   +6 more
wiley   +1 more source

Sport et lien social [PDF]

open access: yesCorps et culture, 1998
openaire   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou   +9 more
wiley   +1 more source

Why frailty and sarcopenia matter to everyone. [PDF]

open access: yesSingapore Med J
Chen CY   +4 more
europepmc   +1 more source

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