Results 111 to 120 of about 1,917,255 (320)

Simulation aided life cycle sustainability assessment framework for manufacturing design and management [PDF]

, 2016
Decision making for sustainable manufacturing design and management requires critical considerations due to the complexity and partly conflicting issues of economic, social and environmental factors.
Gbededo, Mijoh Ayodele, Liyanage, Kapila, Oraifige, Ilias   +2 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Synergistic Effects of Lignocellulosic Baglog Compost and Biochar on Tomato Plant Growth

BioResources
Indonesian agriculture faces multifaceted challenges, particularly the need to enhance productivity while maintaining environmental sustainability to ensure high-quality food production.
Titin Handayani, Septi Syahrani, Ira Nurhayati Djarot, Agusta Samodra Putra, Netty Widyastuti, Akhmad Rifai, Amita Indah Sitomurni, Diana Nurani, Djatmiko Pinardi, Noorwitri Utami, Nuha Nuha, Sri Peni Wijayanti, Ari Kabul Paminto, Anisa Lutfia, Afifah Nurmala Karima, Hanifah Nisrina, Azalea Eugenie, Rizki Amaliyah, Arief Barkah   +18 more
doaj  

A comparative nutritional life cycle assessment of processed and unprocessed soy-based meat and milk alternatives including protein quality adjustment

Frontiers in Sustainable Food Systems
Efforts towards sustainable food systems have stimulated the development of plant-based alternatives to meat and milk. However, the debate on the nutritional quality of (processed) plant products compared to animal products remains unresolved, and ...
Moritz Herrmann, Eric Mehner, Lotti Egger, Reto Portmann, Laila Hammer, Laila Hammer, Laila Hammer, Thomas Nemecek   +7 more
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Journal Staff [PDF]

, 2011
A life cycle assessment (LCA) of a low energy / passive house in northern Sweden, including building materials and energy use is reported. The case study building is semi detached house for two families situated in Östersund (lat. 63°N), Sweden.
Danielski, Itai, Fröling, Morgan, Jonasson, Jonas, Svensson, Michelle   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Adoption model of eco-friendly livestock innovation for beef cattle sustainability in dry climate regions

Environmental and Sustainability Indicators
Beef cattle farming plays an important role in improving rural economies, especially in arid climates that often face complex ecological, social and economic challenges.
Ture Simamora, Paulus Klau Tahuk, Muhamad Nasir Rofiq, Ody Wolfrit Matoneng, Stefanus Sio, Lalu Muhamad Risman Dwi Jumansyah, Brigida Antonia Correia, Ligia Tomas Correia   +7 more
doaj   +1 more source

Organic farming without fossil fuels - life cycle assessment of two Swedish cases [PDF]

, 2013
Organic agriculture is dependent on fossil fuels, just like conventional agriculture, but this can be reduced by the use of on-farm biomass resources. The energy efficiency and environmental impacts of different alternatives can be assessed by life cycle
Baky, A., Hansson, P.-A., Kimming, M., Nordberg, Å., Sundberg, C.   +4 more
core